R. An

Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain

This study identifies ultra-potent Omicron-specific antibodies targeting the N1/N2 loop of the Spike NTD, which neutralize SARS-CoV-2 by competing with ACE2 and blocking S1 shedding, but are evaded by BA.2.86 and BA.2.87.1 sublineages.

Omicron-specific naive B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine

The paper investigates how Omicron-specific naive B cell maturation after breakthrough infection alleviates immune imprinting from inactivated SARS-CoV-2 vaccines.

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

This study analyzes the humoral immune response to SARS-CoV-2 XBB and JN.1 lineages, showing JN.1 elicits superior neutralization and highlights the need for JN.1-based vaccine boosters.

Viral evolution prediction identifies broadly neutralizing antibodies against existing and prospective SARS-CoV-2 variants

This paper predicts SARS-CoV-2 RBD evolution using deep mutational scanning to identify broadly neutralizing antibodies effective against existing and prospective variants.

Large-scale multi-omics analyses identified root-microbiome associations underlying plant nitrogen nutrition

The paper identifies root-microbiome associations affecting plant nitrogen nutrition through multi-omics analyses of 1,341 rapeseed samples.

Motion Blur Microscopy

This paper introduces motion blur microscopy to image cell adhesion in whole blood flow without dilution, enabling analysis of adhesion dynamics in physiological conditions.

Antigenicity and infectivity characterization of SARS-CoV-2 BA.2.86

This study characterizes the antigenic properties and infectivity of the SARS-CoV-2 BA.2.86 variant, finding it evades immune responses but has reduced infectivity compared to previous variants.

Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding

This study shows that convergent evolution of SARS-CoV-2 XBB lineages at RBD positions 455-456 synergistically enhances antibody evasion and ACE2 binding through epistatic interactions.

Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

This study shows repeated Omicron exposures reduce immune imprinting from wildtype vaccines, leading to higher neutralizing antibodies against XBB variants.

Catch bonds in sickle cell disease: shear-enhanced adhesion of red blood cells to laminin

This paper investigates catch bonding in sickle cell disease by measuring RBC adhesion dynamics to laminin under shear flow, revealing patient-specific variations in bond strength and clinical relevance.

Extinction drives a discontinuous temporal pattern of species-area relationships in a microbial microcosm system

This study shows that extinction drives a temporally discontinuous species-area relationship in microbial microcosms, with small-scale extinctions promoting stability and mass extinctions resetting the system.

Assessment of infant outgrowth of cow's milk allergy in relation to the faecal microbiome and metaproteome

This study examines the relationship between the faecal microbiome and metaproteome and the outgrowth of cow's milk allergy in infants over 12 months.

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

The paper shows that convergent evolution of Omicron variants evades antibodies from BA.5 infections while maintaining ACE2 binding, driven by immune imprinting.

Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents

The paper identifies a potent and broad sarbecovirus-neutralizing antibody cocktail, SA55+SA58, from SARS convalescents to combat Omicron variants and other fast-evolving viruses.

Characterizations of enhanced infectivity and antibody evasion of Omicron BA.2.75

This study characterizes the enhanced infectivity and antibody evasion properties of the SARS-CoV-2 Omicron subvariant BA.2.75 compared to BA.5 and other variants.

Sickle red blood cell derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor

This study shows that sickle RBC-derived extracellular vesicles activate endothelial cells and enhance RBC adhesion via von Willebrand factor, with implications for SCD treatment.

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

This study investigates antibody evasion by SARS-CoV-2 Omicron sublineages BA.2.12.1, BA.4, and BA.5 against plasma from vaccination and BA.1 infection, showing increased neutralization escape.

E. coli can eat DNA as excellent nitrogen source to grow quickly

This study shows E. coli can use DNA as a nitrogen source for growth, outperforming Bifidobacterium bifidum, and ingests long DNA directly without altering its length.

Omicron BA.2 specifically evades broad sarbecovirus neutralizing antibodies

This study shows that BA.2 causes stronger antibody evasion than BA.1, particularly in SARS convalescents, and identifies key mutations responsible for this escape.

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

This study identifies how Omicron evades neutralizing antibodies by analyzing mutations and their effects on different epitope groups, showing over 85% of tested antibodies are escaped.

Intracellular Optical Doppler Phenotypes of Chemosensitivity in Human Epithelial Ovarian Cancer

The paper develops an assay using Doppler spectroscopy to predict chemotherapy response in ovarian cancer by analyzing intracellular motion in tumor tissues.

Morphologic Classification and Automatic Diagnosis of Bacterial Vaginosisby Deep Neural Networks

This paper develops CNN models to automatically classify Nugent scores from vaginal microscopy images, achieving higher accuracy than human experts.

One New Species of the Genus Dryomys (Rodentia, Glirgae) from Xinjiang China, Dryomys Yarkandensis sp. nov

The paper describes a new species of rodent, Dryomys yarkandensis, discovered in Xinjiang, China, and compares it to other Dryomys species based on morphological characteristics.