Author

D. McCarthy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. Alassaf· 1 shared A. Asangba· 1 shared A. Cantu· 1 shared A. Cazares· 1 shared A. Jones· 1 shared A. Kurilshikov· 1 shared A. Lin· 1 shared A. Reyes· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. Alassaf

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bioinformatic and Experimental Characterization of the RBM15 RNA Binding Protein

E. Bose, C. Mayes, L. Ellis, C. Baker, S. Tambalotti, B. Eusse, S. Xiong, Y. P. O. Sarpong, M. Shalaby, L. Barry, F. Lewis, J. Joseph, T. Isaacs, D. McCarthy, D. Katz, , A. Jones

This study characterizes RBM15's RNA binding mechanism through bioinformatics and experiments, showing it interacts with stem-loop RNA motifs via RRMs 2 and 3.

bioRxiv · Jul 20, 2023Biochemistry

TaqMan Array Cards enable monitoring of diverse enteric pathogens across environmental and host reservoirs

R. Lappan, R. Henry, S. L. Chown, S. P. Luby, E. Higginson, L. Bata, T. Jirapanjawat, C. Schang, J. J. Openshaw, J. O'Toole, A. Lin, A. Tela, T. H. F. Wong, M. A. French, R. R. Brown, , D. McCarthy

This study compares TaqMan Array Cards and standard qPCR for detecting enteric pathogens in diverse samples, finding comparable performance with TAC offering a broader panel at lower cost.

bioRxiv · Oct 27, 2020 · PreprintMicrobiology

Validation of a CRISPR/cas9-based technology platform for examining specific immune gene functions in an experimental murine model of IBD

R. Wang, S. Graham, N. Sun, D. McCarthy, R. Peng, J. Erickson, X. Zhu, M. A. Wurbel, R. Dunstan, N. Chung, E. Fiebiger, T. Ghayur, J. Gu

The paper validates a CRISPR/Cas9 platform for studying immune gene functions in a murine IBD model, demonstrating its utility for in vivo validation of therapeutic targets.

bioRxiv · Apr 26, 2019 · PreprintImmunology

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

R. Edwards, A. Vega, H. Norman, M. C. Ohaeri, K. Levi, E. Dinsdale, O. Cinek, R. Aziz, K. McNair, J. Barr, K. Bibby, S. Brouns, A. Cazares, P. A. de Jonge, C. Desnues, , Doane

This study investigates the origin, evolution, and epidemiology of crAssphage, a widespread human gut virus, using global DNA sequences showing local phylogeographic clustering and ancient primate associations.

bioRxiv · Jan 26, 2019Microbiology