Author

D. Raj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

G. Kao· 3 shared P. Naredi· 3 shared A. Podraza-Farhanieh· 2 shared A. Dasgupta· 1 shared A. Kaushik· 1 shared A. LAHIRI· 1 shared A. Podraza· 1 shared A. V. Nair· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCell Biology

G. Kao

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4 papers

Recent·Most cited

Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth

D. Raj, A. V. Nair, J. Sharma, S. Prakash, A. Kaushik, S. Basu, S. Sahu, S. Singh, V. Bhosale, T. Chandra, U. C. Ghoshal, A. Dasgupta, M. I. Siddiqi, S. K. Gupta, D. Chakravortty, , A. LAHIRI

The paper shows Salmonella effector SseI recruits peroxisomes to SCVs, activates ARF-1, and facilitates cholesterol transport for bacterial growth.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Non-overlapping requirements of ASNA-1 function for insulin secretion, cisplatin resilience, and growth revealed by genetic analysis of point mutants in C. elegans

D. Raj, A. Podraza-Farhanieh, P. Gallego, G. Kao, P. Naredi

bioRxiv · Jul 12, 2022 · PreprintCell Biology

Proinsulin dependent interaction between ENPL-1/GRP94 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans.

A. Podraza-Farhanieh, D. Raj, G. Kao, P. Naredi

The paper identifies a proinsulin-dependent interaction between ENPL-1/GRP94 and ASNA-1 in neurons that is essential for insulin secretion in C. elegans and linked to diabetes in mammals.

bioRxiv · Jun 15, 2022 · PreprintCell Biology

ASNA-1 oxidation induced by cisplatin exposure enhances its cytotoxicity by selectively perturbing tail anchored protein targeting

D. Raj, O. Billing, A. Podraza, O. Hemmingsson, G. Kao, P. Naredi

This paper shows that cisplatin-induced oxidation of ASNA-1 disrupts tail-anchored protein targeting, leading to ER dysfunction and increased cisplatin sensitivity in C. elegans.

bioRxiv · Oct 28, 2019 · PreprintCell Biology