Hachiman is a genome integrity sensor
O. T. Tuck, B. A. Adler, E. G. Armbruster, A. Lahiri, J. J. Hu, J. Zhou, J. Pogliano, J. A. Doudna
This study identifies Hachiman as a bacterial antiphage defense system that degrades all DNA in response to DNA damage, revealing its role as a genome integrity sensor.
bioRxiv · Feb 29, 2024 · PreprintBiochemistry