Author

D. Rychkov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. M. Sarwal· 2 shared M. Sirota· 2 shared A. A. da Silva· 1 shared A. Carvidi· 1 shared A. Gross· 1 shared A. J. Butte· 1 shared A. L. Lourenco· 1 shared A. Lee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

M. M. Sarwal

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Author profile →

4 papers

Recent·Most cited

Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencing

M. Binvignat, B. Miao, C. Wibrand, M. Yang, D. Rychkov, E. Flynn, J. Nititham, W. Tamaki, U. Khan, A. Carvidi, M. Krueger, E. Niemi, Y. Sun, G. K. Fragiadakis, J. Sellam, , M. Sirota

This study uses single-cell RNA sequencing of PBMCs from RA patients and controls to identify disease-associated cell subsets and gene signatures linked to RA disease activity.

bioRxiv · Oct 5, 2023 · PreprintImmunology

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.

P. Rashmi, T. K. Sigdel, D. Rychkov, I. Damm, A. A. da Silva, F. Vincenti, A. L. Lourenco, C. S. Craik, J. Reiser, M. M. Sarwal

This paper investigates how circulating factors like suPAR and CD40 autoantibodies induce podocyte injury in FSGS and identifies therapeutic targets for rFSGS.

bioRxiv · Sep 8, 2022Immunology

Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses

T. Hagan, B. Gerristen, L. E. Tomalin, S. Fourati, M. P. Mule, D. G. Chawla, D. Rychkov, E. Henrich, H. E. Miller, J. Diray-Arce, P. Dunn, A. Lee, The Human Immunology Project Consortium (HIPC), O. Levy, R. Gottardo, , B. Pulendran

The paper integrates transcriptional data from 13 vaccines to identify a time-adjusted signature predicting antibody responses across different vaccines.

bioRxiv · Apr 20, 2022Immunology

Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis

J. Ashouri, L.-Y. Hsu, S. Yu, D. Rychkov, Y. Chen, D. Chang, M. Sirota, E. Hansen, L. Lattanza, J. Zikherman, A. Weiss

The paper identifies arthritogenic CD4 T cells in murine and human autoimmune arthritis using Nur77 as a marker of TCR signaling.

bioRxiv · Mar 12, 2019Immunology