Author

S. Bea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:machine learning (classical)· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Campo· 3 shared F. Nadeu· 3 shared E. Gine· 2 shared J. Lu· 2 shared T. Zenz· 2 shared X. S. Puente· 2 shared A. Diaz-Navarro· 1 shared A. Lopez-Guillermo· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

E. Campo

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Author profile →

4 papers

Recent·Most cited

RFcaller: a machine learning approach combined with read-level features to detect somatic mutations

A. Diaz-Navarro, P. Bousquets-Munoz, F. Nadeu, S. Lopez-Tamargo, S. Bea, E. Campo, X. S. Puente

RFcaller uses machine learning with read-level features to detect somatic mutations accurately and efficiently in tumor-normal paired samples.

bioRxiv · May 11, 2022 · PreprintCancer Biology

Targeted Reactivation of X-linked Endogenous FOXP3 Gene from X-chromosome Inactivation in Human Female Breast Cancer Cells

X. Cui, Z. Xu, S. Wang, X. Li, E. Stringer-Reasor, S. Bea, L. Zeng, D. Zhao, R. Liu, L. S. Qi, L. Wang

This paper develops a CRISPRi/a approach to reactivate FOXP3 and silence XIST from XCI in human breast cancer cells, showing enhanced epigenetic changes and therapeutic potential.

bioRxiv · Aug 14, 2021Cancer Biology

SAMHD1 mutations in mantle cell lymphoma are recurrent and confer in vitro resistance to nucleoside analogues

M. M. Bühler, J. Lu, S. Scheinost, F. Nadeu, D. Roos-Weil, M. Hensel, T. Thavayogarajah, H. Moch, M. G. Manz, E. Haralambieva, E. Marques Maggio, S. Bea, E. Gine, E. Campo, O. A. Bernard, , T. Zenz

bioRxiv · Jun 9, 2020Cancer Biology

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome

M. Duran-Ferrer, G. Clot, F. Nadeu, R. Beekman, T. Bauman, J. Nordlund, Y. Marincevic-Zuniga, G. Lonnerholm, A. Rivas, S. Martin, R. Ordonez, G. Castellano, M. Kulis, A. Queiros, L. Seung-Tae, , J. I. Martin-Subero

This study analyzes DNA methylation in B-cell tumors to show its relation to proliferative history and clinical outcomes, introducing a new mitotic clock for prognosis.

bioRxiv · Feb 6, 2020Cancer Biology