E. Fleming

Species- and strain-effects in interferon, innate immunity, and barrier transcriptional response of microbiome interactions of 3D respiratory epithelial cultures

The paper examines how different microbes affect host immune and barrier responses in respiratory epithelial cultures, finding that interferon variability is not linked to microbial diversity or other innate pathways.

High-Throughput Bioprinting of the Nasal Epithelium using Patient-derived Nasal Epithelial Cells

This study uses 3D bioprinting to create nasal epithelium models from patient-derived cells, enabling high-throughput fabrication and recapitulating native epithelial architecture and virus infection capability.

Assessing the impact of successive soil cultivation on Meloidogyne enterolobii infection and on soil bacterial assemblages

This study evaluates how repeated soil cultivation affects Meloidogyne enterolobii infection and soil bacterial communities in two different agricultural soils over two experiments.

Measuring prion propagation in single bacteria elucidates mechanism of loss

The paper investigates prion propagation in single bacterial cells, finding that prions are lost through random partitioning during division and that a stochastic model recapitulates observed properties.

Multi-omics of host-microbiome interactions in short- and long-term Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

This study uses multi-omics analyses to compare short- and long-term ME/CFS patients with healthy controls, identifying microbiome and metabolic differences and potential biomarkers.

Mice with a humanized immune system are resilient to transplantation of human microbiota

This study shows that humanized mice with engrafted human immune cells can resist human gut microbes, but microbial communities differ from those in non-humanized mice.

Large-scale CRISPRi and transcriptomics of Staphylococcus epidermidis identify genetic factors implicated in commensal-pathogen lifestyle versatility

This study uses CRISPRi and transcriptomics to identify genetic factors in S. epidermidis that contribute to its commensal and pathogenic lifestyle versatility across diverse environments.

Species and strain cultivation of skin, oral, and gut microbiota

The paper describes a workflow for cultivating skin, oral, and gut microbes using metagenomic data and validates its effectiveness.