Author

E. L. Reinherz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Kim· 2 shared T. Walz· 2 shared W. Hwang· 2 shared Y. Wang· 2 shared A. Akitsu· 1 shared C. M. Messier· 1 shared G. Hiotis· 1 shared H. Richter· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

M. Kim

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedNov 8, 2023

Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility

K. Tan, J. Chen, Y. Kaku…·M. Kim

The paper shows that HIV-1 MPER-targeting antibodies generated by vaccines lack structural constraints needed to access the MPER, despite having bnAb-like paratopes.

DOI 10.1038/s41467-023-42097-6

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivMay 9, 2022

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

S. Yang, G. Hiotis, Y. Wang…·T. Walz

The paper investigates HIV-1 spike protein dynamics using cryo-EM and simulations, showing how tilting exposes the MPER to antibody attack and alters membrane fusion.

DOI 10.1038/s41467-022-34008-y

viruscryo-EM

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ImmunologybioRxivApr 28, 2022

Pre-T cell receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation

J. S. Duke-Cohan, A. Akitsu, R. J. Mallis…·E. L. Reinherz

The paper shows that preTCR-pMHC interactions prevent thymocyte dedifferentiation by analyzing single-cell transcriptomes in fetal thymic cultures with and without pMHC.

DOI 10.1038/s41586-022-05555-7

mousebulk RNA-seq

𝕏 PostBluesky