Author

E. Patrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 5 Assay:spatial transcriptomics· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:spatial domain detection· 3 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

U. Palendira· 3 shared A. Di Re· 2 shared A. L. Ferguson· 2 shared A. N. Harman· 2 shared C. E. Palme· 2 shared G. Ctercteko· 2 shared H. Baharlou· 2 shared J. H. Lee· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

U. Palendira

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Spatial mapping reveals unique cellular interactions and enhanced tertiary lymphoid structures in responders to anti-PD-1 therapy in mucosal head and neck cancers.

A. L. Ferguson, T. Beddow, E. Patrick, E. Willie, M. S. Elliott, T.-H. Low, J. Wykes, M. H. Hui, C. E. Palme, M. Boyer, J. R. Clark, J. H. Lee, U. Palendira, R. Gupta

The paper identifies immune landscape differences in responders and non-responders to anti-PD-1 therapy in head and neck cancers using spatial mapping.

bioRxiv · Apr 18, 2024 · PreprintCancer Biology

Spatial mapping of human lung tissue reveals granuloma diversity and histopathological superstructure in tuberculosis

A. J. Sawyer, E. Patrick, J. Edwards, J. S. Wilmott, T. Fielder, Q. Yang, D. L. Barber, J. D. Ernst, W. J. Britton, U. Palendira, X. Chen, C. G. Feng

This study maps spatial immune cell composition in human TB lung tissue, revealing diverse non-necrotizing aggregates surrounding necrotizing granulomas.

bioRxiv · Jul 31, 2022 · PreprintImmunology

An in situ quantitative map of initial human colorectal HIV transmission

H. Baharlou, N. P. Canete, E. E. Vine, k. hu, D. Yuan, K. J. Sandgren, K. M. Bertram, `Najla Nasr, J. W. Rhodes, M. Gosselink, A. Di Re, F. Reza, G. Ctercteko, N. ` Pathma-Nathan, G. Collins, , A. N. Harman

This study quantifies HIV transmission dynamics in human colorectal tissue, showing HIV localizes to mucosal dendritic cells and submucosal macrophages rather than CD4+ T-cells.

bioRxiv · Apr 30, 2022Immunology

High-dimensional and spatial analysis reveals immune landscape dependent progression in cutaneous squamous cell carcinoma

A. L. Ferguson, A. R. Sharman, R. O. Allen, T. Ye, J. H. Lee, T.-H. H. Low, S. Ch'ng, C. E. Palme, B. Ashford, M. Ranson, j. R. Clark, E. Patrick, R. Gupta, U. Palendira

This study compares immune landscapes of non-progressing and progressing cutaneous squamous cell carcinomas to identify immune features associated with metastasis.

bioRxiv · Apr 19, 2022Pathology

Identification of HIV-Transmitting Sub-Epithelial Mononuclear Phagocytes in Human Anogenital and Colorectal Tissues

J. W. Rhodes, R. A. Botting, K. M. Bertram, H. Rana, H. Baharlou, E. E. Longmuir-Vine, P. Vegh, J. Fletcher, T. R. O'Neil, G. P. Parnell, D. Graham, N. Nasr, J. J. K. Lim, L. Barnouti, P. Haertsch, , A. N. Harman

This study identifies two sub-epithelial mononuclear phagocyte subsets that preferentially uptake and transmit HIV to CD4 T cells in anogenital and colorectal tissues.

bioRxiv · May 26, 2020 · PreprintImmunology

PGRMC1 phosphorylation and cell plasticity 1: glycolysis, mitochondria, tumor growth

B. M. Thejer, P. P. Adhikary, A. Kaur, S. L. Teakel, A. Van Oosterum, I. Seth, M. Pajic, K. M. Hannan, M. Pavy, P. Poh, J. A. Jazayeri, T. Zaw, D. Pascovici, M. Ludescher, M. Pawlak, , M. A. Cahill

This study shows that altering PGRMC1 phosphorylation in cancer cells affects energy metabolism, mitochondrial function, and tumor growth.

bioRxiv · Sep 6, 2019Cancer Biology