Author

E. Scadden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

A. Vu· 1 shared B. Choi· 1 shared C. P. Reynolds· 1 shared D. M. Booth· 1 shared D. Scadden· 1 shared D. Sykes· 1 shared E. L. Carpenter· 1 shared E. Nakamaru-Ogiso· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Vu

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Author profile →

2 papers

Recent·Most cited

REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE

J. Coku, D. M. Booth, J. Skoda, M. C. Pedrotty, J. Vogel, K. Liu, A. Vu, E. L. Carpenter, J. C. Ye, M. A. Chen, P. Dunbar, E. Scadden, E. Nakamaru-Ogiso, Y. Li, K. C. Goldsmith, , M. D. Hogarty

The paper identifies reduced ER-mitochondria contacts as a mechanism promoting neuroblastoma multidrug resistance by impairing Ca2+ transfer and apoptosis.

bioRxiv · Mar 1, 2021Cancer Biology

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

N. Baryawno, Y. Kfoury, N. Severe, S. Mei, K. U. Gustafsson, T. Hirz, T. Brouse, E. Scadden, B. Choi, N. Barkas, J. Shin, P. Saylor, D. Scadden, D. Sykes, P. Kharchenko

The paper identifies an immunosuppressive microenvironment in human prostate cancer bone metastases and shows that disrupting the CCL20-CCR6 axis can restore T cell reactivity and improve survival in mice.

bioRxiv · Mar 19, 2020 · PreprintCancer Biology