Author

P. Kharchenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Kumanogoh· 1 shared A. Pradeep· 1 shared A. Scialdone· 1 shared B. Choi· 1 shared B. Gottgens· 1 shared C. Burns· 1 shared C. Juhlin· 1 shared C. Larsson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. Kumanogoh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence

D. Toghani, S. Zeng, E. Mahammadov, E. I. Crosse, N. Seyedhassantehrani, C. Burns, D. Gravano, S. Radtke, H.-P. Kiem, S. Rodriguez, N. Carlesso, A. Pradeep, N. K. Wilson, S. J. Kinston, B. Gottgens, , L. Silberstein

This study identifies Sema4A as a critical niche factor required for myeloid-biased HSC self-renewal and long-term persistence under stress.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumors.

O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. Juhlin, P. Kogner, S. Schlisio

The paper identifies distinct cellular identities in low and high-risk neuroblastoma tumors using single-nuclei transcriptomes, linking them to clinical outcomes and age at diagnosis.

bioRxiv · Mar 26, 2021Cancer Biology

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

N. Baryawno, Y. Kfoury, N. Severe, S. Mei, K. U. Gustafsson, T. Hirz, T. Brouse, E. Scadden, B. Choi, N. Barkas, J. Shin, P. Saylor, D. Scadden, D. Sykes, P. Kharchenko

The paper identifies an immunosuppressive microenvironment in human prostate cancer bone metastases and shows that disrupting the CCL20-CCR6 axis can restore T cell reactivity and improve survival in mice.

bioRxiv · Mar 19, 2020 · PreprintCancer Biology