Author

F. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Arabidopsis· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

F. Ginhoux· 2 shared H. Jia· 2 shared H. Wang· 2 shared L. SuniD· 2 shared X. Cai· 2 shared Y. Shi· 2 shared Y. Sun· 2 shared Z. Liu· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

F. Ginhoux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CCR7+ Dendritic Cells Define a Type 17 Module in Psoriasis

Y. Sun, F. Lou, X. Cai, Z. Wang, X. Yang, L. Sun, Z. Wu, Z. Liu, Y. Shi, F. Ginhoux, H. Wang

The paper identifies CCR7+ dendritic cells as the primary source of IL-23 in psoriasis, linking them to type 17 inflammation and relapse.

bioRxiv · Apr 28, 2024 · PreprintImmunology

Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Endosomal Sensing by Dendritic Cells in Psoriasis

F. Lou, Y. Sun, Z. Xu, L. Niu, Z. Wang, S. Deng, Z. Liu, H. Zhou, J. Bai, Q. Yin, X. Cai, L. Sun, H. Wang, Z. Wu, X. Chen, , H. Wang

This study shows that excessive polyamine production in keratinocytes drives self-RNA sensing by dendritic cells, contributing to psoriasis inflammation.

bioRxiv · Mar 9, 2020Immunology

A decoy heterotrimeric Gα protein has substantially reduced nucleotide binding but retains nucleotide-independent interactions with its cognate RGS protein and Gβγ dimer

F. Lou, T. M. Abramyan, H. Jia, A. Tropsha, A. M. Jones

This paper shows that Arabidopsis XLG2 has reduced nucleotide binding but maintains interactions with RGS and Gβγ, suggesting it functions as a dominant negative G protein.

bioRxiv · Oct 6, 2019Biochemistry

Biased Signaling: Distinct Ligand-directed Plasma Membrane Signalsomes Using a Common RGS/G Protein Core

T. Ross-Elliott, J. Watkins, X. Shan, F. Lou, B. Dreyer, M. Tunc-Ozdemir, H. Jia, J. Yang, L. Wu, Y. Trusov, P. Krysan, A. Jones

The paper identifies distinct ligand-directed plasma membrane signalsomes in Arabidopsis that drive biased signaling through compartmentation and different trafficking origins.

bioRxiv · Aug 28, 2019 · PreprintPlant Biology