Author

N. L. Garza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Organism:non-human primate· 1

Frequent Co-Authors

R. F. Johnson· 4 shared A. Sher· 3 shared B. A. P. Lafont· 3 shared C. S. Clancy· 3 shared K. D. Mayer-Barber· 3 shared K. L. Hilligan· 3 shared S. D. Oland· 3 shared S. Namasivayam· 3 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersImmunology

R. F. Johnson

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Author profile →

5 papers

Recent·Most cited

Pre-existing interferon gamma conditions the lung to mediate early control of SARS-CoV-2

K. L. Hilligan, S. Namasivayam, C. S. Clancy, P. J. Baker, S. I. Old, V. Peluf, E. P. Amaral, S. D. Oland, D. O'Mard, J. Laux, M. Cohen, N. L. Garza, B. Lafont, R. F. Johnson, C. G. Feng, , A. Sher

This study shows that pre-existing IFN-gamma responses from bacterial infection reduce SARS-CoV-2 viral loads in the lungs and protect against disease in mice.

bioRxiv · Jul 15, 2023 · PreprintImmunology

Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation

K. L. Hilligan, O. O. Oyesola, S. Namasivayam, N. Howard, C. S. Clancy, S. D. Oland, N. L. Garza, B. A. P. Lafont, R. F. Johnson, K. D. Mayer-Barber, A. Sher, P. Loke

This study shows that prior helminth infection reduces SARS-CoV-2 viral loads in mice by enhancing CD8+ T cell responses through macrophage-dependent mechanisms.

bioRxiv · Nov 9, 2022 · PreprintImmunology

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

C. E. Nelson, T. W. Foreman, K. D. Kauffman, S. Sakai, S. T. Gould, J. D. Fleegle, F. Gomez, NIAID/DIR Tuberculosis Imaging Program, C. Le Nouen, X. Liu, T. L. Burdette, N. L. Garza, B. A. P. Lafont, K. Brooks, C. S. L. Arlehamn, , D. L. Barber

This study examines the roles of IFNγ and IL-10 in SARS-CoV-2 infection of rhesus macaques, finding IL-10 suppresses T cell expansion but promotes tissue-resident memory cell formation.

bioRxiv · Sep 13, 2022Immunology

Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques

C. Le Nouen, C. E. Nelson, X. Liu, H.-S. Park, Y. Matsuoka, C. Luongo, C. Santos, L. Yang, R. Herbert, A. Castens, I. N. Moore, T. Wilder-Kofie, R. Moore, A. Walker, P. Zhang, , U. J. Buchholz

This study evaluates an intranasal parainfluenza virus-vectored SARS-CoV-2 vaccine in macaques, showing it induces mucosal and systemic immunity and protects against viral challenge.

bioRxiv · May 21, 2022Immunology

Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge

K. L. Hilligan, S. Namasivayam, C. S. Clancy, D. O'Mard, S. D. Oland, S. J. Robertson, P. J. Baker, E. Castro, N. L. Garza, B. A. P. Lafont, R. Johnson, F. Ronchese, K. D. Mayer-Barber, S. M. Best, A. Sher

This study shows that intravenous BCG vaccination protects mice from lethal SARS-CoV-2 infection by altering pulmonary myeloid cell function and reducing immunopathology.

bioRxiv · Aug 30, 2021Immunology