Author

E. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 6 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:ecology & biodiversity· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

K. D. Mayer-Barber· 5 shared P. J. Baker· 5 shared K. L. Hilligan· 4 shared A. C. Bohrer· 3 shared D. L. Barber· 3 shared A. D. Klion· 2 shared A. Sher· 2 shared B. B. Andrade· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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5 shared papersImmunology

K. D. Mayer-Barber

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

P. J. Baker, A. C. Bohrer, E. Castro, E. P. Amaral, M. Snow-Smith, F. Torres-Juarez, S. T. Gould, A. T. Queiroz, E. R. Fukutani, C. M. Jordan, J. S. Khillan, K. Cho, D. L. Barber, B. B. Andrade, R. F. Johnson, , K. D. Mayer-Barber

This study shows that pre-existing lung inflammation reduces SARS-CoV-2 replication by activating innate immune pathways, highlighting the role of the inflammatory microenvironment in controlling viral infection.

bioRxiv · Mar 27, 2024Immunology

Evaluation of endogenous and therapeutic 25-hydroxycholesterols in murine models of pulmonary SARS-CoV-2 infection

M. B. Fessler, J. Madenspacher, P. J. Baker, K. L. Hilligan, E. Castro, J. Meacham, S.-H. Chen, R. F. Johnson, N. P. Martin, C. J. Tucker, D. Mahapatra, M. Cesta, K. D. Mayer-Barber

This study evaluates the antiviral and inflammatory effects of 25-hydroxycholesterol and its metabolite in murine SARS-CoV-2 models, finding no significant antiviral activity and potential pro-injury effects.

bioRxiv · Sep 12, 2022 · PreprintImmunology

An outbreak of SARS-CoV-2 in big hairy armadillos (Chaetophractus villosus) associated with Gamma variant in Argentina three months after being undetectable in humans

F. E. Lucero Arteaga, M. Nabaes Jodar, M. Mondino, A. Portu, M. Boeris, A. Jolly, A. M. Jar, S. L. Mundo, E. Castro, D. Alvarez, C. Torres, M. Viegas, A. Bratanich

The paper reports SARS-CoV-2 Gamma variant infection in big hairy armadillos in Argentina three months after its last detection in humans, highlighting potential viral reservoirs.

bioRxiv · Aug 23, 2022 · PreprintMicrobiology

Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

A. C. Bohrer, E. Castro, C. E. Tocheny, M. Assmann, B. Schwarz, E. Bohrnsen, M. A. Makiya, F. Legrand, K. L. Hilligan, P. J. Baker, F. Torres-Juarez, Z. Hu, H. Ma, L. Wang, L. Niu, , K. D. Mayer-Barber

This study shows that eosinophils migrate to the lungs early after Mycobacterium tuberculosis infection in mice and macaques, mediated by GPR183 and Ch25h, independent of CCR3.

bioRxiv · Feb 18, 2022Immunology

Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge

K. L. Hilligan, S. Namasivayam, C. S. Clancy, D. O'Mard, S. D. Oland, S. J. Robertson, P. J. Baker, E. Castro, N. L. Garza, B. A. P. Lafont, R. Johnson, F. Ronchese, K. D. Mayer-Barber, S. M. Best, A. Sher

This study shows that intravenous BCG vaccination protects mice from lethal SARS-CoV-2 infection by altering pulmonary myeloid cell function and reducing immunopathology.

bioRxiv · Aug 30, 2021Immunology

Eosinophils are an integral component of the pulmonary granulocyte response in Tuberculosis and promote host resistance in mice

A. C. Bohrer, E. Castro, Z. Hu, A. T. L. Queiroz, C. E. Tocheny, M. Assmann, S. Sakai, C. Nelson, P. J. Baker, H. Ma, L. Wang, W. Zilu, E. du Bruyn, C. Riou, K. D. Kauffman, , K. D. Mayer-Barber

This study shows eosinophils are recruited to tuberculosis-infected lung tissue in mice and contribute to host resistance against Mtb infection.

bioRxiv · May 29, 2021Immunology

Shark movements in the Revillagigedo Archipelago and connectivity with the Eastern Tropical Pacific

F. Lara Lizardi, M. Hoyos-Padilla, A. Hearn, A. P. Klimley, F. Galvan-Magana, R. Arauz, S. Bessudo, E. Castro, E. Clua, E. Espinoza, C. Fischer, C. Penaherrera-Palma, T. Steiner, J. T. Ketchum

The paper tracks shark movements between islands in the Revillagigedo Archipelago and the Eastern Tropical Pacific to assess connectivity and migration patterns.

bioRxiv · Mar 2, 2020 · PreprintEcology