K. D. Mayer-Barber

This study shows that pre-existing IFN-gamma responses from bacterial infection reduce SARS-CoV-2 viral loads in the lungs and protect against disease in mice.

This study identifies a monocyte-intrinsic TNF-IL-1 circuit that controls Yersinia infection within intestinal granulomas by signaling to non-hematopoietic cells.

This study shows that prior helminth infection reduces SARS-CoV-2 viral loads in mice by enhancing CD8+ T cell responses through macrophage-dependent mechanisms.

This study compares inflammatory profiles in blood and pericardial fluid of HIV-1-infected individuals with latent TB, PTB, and PCTB, finding site-specific elevation of analytes and HLA-DR as a better TB diagnostic marker.

This study evaluates the antiviral and inflammatory effects of 25-hydroxycholesterol and its metabolite in murine SARS-CoV-2 models, finding no significant antiviral activity and potential pro-injury effects.

This study compares Mtb-specific CD4 T cell profiles in pericardial fluid and blood from PCTB patients, finding distinct phenotypes in PCF with no difference in cytokine production.

This study shows that eosinophils migrate to the lungs early after Mycobacterium tuberculosis infection in mice and macaques, mediated by GPR183 and Ch25h, independent of CCR3.

This study shows that intravenous BCG vaccination protects mice from lethal SARS-CoV-2 infection by altering pulmonary myeloid cell function and reducing immunopathology.

This study shows eosinophils are recruited to tuberculosis-infected lung tissue in mice and contribute to host resistance against Mtb infection.

The paper shows that IL-1R1-dependent signals enhance clearance of cytosolic mycobacteria in vivo, particularly when host immunity is compromised.

This study shows that PD-1 blockade worsens Mycobacterium tuberculosis infection in rhesus macaques by increasing bacterial loads and altering immune responses.