Microsporidia Ser/Thr Protein Phosphatase PP1 Targets DCs MAPK Pathway and Impairs Immune Functions
J. Bao, Y. Tang, Y. Chen, J. Jin, X. Wang, G. An, L. Cao, H. Zhang, G. Cheng, G. Pan, Z. Zhou
This study shows that Microsporidia infection impairs dendritic cell functions by targeting the p38/MAPK pathway via PP1, increasing susceptibility to secondary infections.
bioRxiv · Sep 13, 2023 · PreprintMicrobiology