Author

G. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Amini· 1 shared A. Cerutti· 1 shared A. Coley· 1 shared A. D. Polydorides· 1 shared A. Dunn· 1 shared A. Krek· 1 shared A. Livanos· 1 shared A. Manning· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperEvolutionary Biology

A. Amini

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolution of a biological thermocouple by adaptation of cytochrome c oxidase in asubterrestrial metazoan

M. N. Guerin, T. S. Ellis, M. J. Ware, A. Manning, A. Coley, A. Amini, G. Chung, K. C. Gunsalus, J. R. Bracht

This study identifies a temperature-sensing adaptation in the cytochrome c oxidase of the Devil Worm, Halicephalobus mephisto, showing how evolutionary changes in mitochondrial function enable temperature-dependent metabolic regulation.

bioRxiv · Dec 5, 2023 · PreprintEvolutionary Biology

Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation

S. J. Kunnen, G. Callegaro, J. J. Sutherland, P. Trairatphisan, H. van Kessel, L. S. Wijaya, G. Chung, K. Pye, K. M. Goldstein, C. R. Teague, C. P. Fisher, J. Saez-Rodriguez, C. Brown, S. A. Elmore, K. M. Heinz-Taheny, , B. van de Water

This study builds gene co-expression networks from rat kidney toxicogenomics data and integrates them into a web tool to improve safety assessment and biomarker identification for drug development.

bioRxiv · Nov 3, 2023 · PreprintPharmacology & Toxicology

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis

P. Canales-Herrerias, M. Uzzan, A. Seki, R. S. Czepielewski, B. Verstockt, A. Livanos, F. Raso, A. Dunn, D. Dai, A. Wang, Z. Al-taie, J. Martin, H. M. Ko, M. Tokuyama, M. Tankelevich, , S. Mehandru

This study investigates the mechanism of vedolizumab in ulcerative colitis by analyzing immune cell changes in gut-associated lymphoid tissue and shows that targeting GALT is a novel mechanism of action.

bioRxiv · Jan 19, 2023Immunology

Novel regulation of the transcription factor ZHX2 by N-terminal methylation

M. M. Conner, H. V. Parker, D. R. Falcone, G. Chung, C. Schaner Tooley

This study identifies ZHX2 as a target of NRMT1 N-methylation, showing its misregulation contributes to liver degeneration in Nrmt1-/- mice.

bioRxiv · Oct 22, 2021Biochemistry

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

P. G. Cipriani, O. Bay, J. P. Zinno, M. Gutwein, H. H. Gan, V. Mayya, G. Chung, J. Chen, H. Fahs, Y. Guan, T. Duchaine, M. Selbach, F. Piano, K. Gunsalus

This study identifies MIP-1 and MIP-2 as C. elegans germ granule proteins that recruit Vasa homolog GLH-1 and are essential for granule formation and germ line development.

bioRxiv · Jun 17, 2021Cell Biology