R. Fernandes

Introducing Isotopia: a stable isotope database for Classical Antiquity

The paper introduces Isotopia, a database of stable isotope measurements from Classical Antiquity, highlighting data gaps and emphasizing the need to address them for better reuse of the data.

Proximity proteomics reveals UCH-L1 as an NLRP3 interactor that modulates IL-1β production in human macrophages and microglia

The paper identifies UCH-L1 as an NLRP3 interactor that modulates IL-1β production in human macrophages and microglia through proximity proteomics and functional assays.

Recent land use and land cover pressures on Iberian peatlands

This study analyzes land use and land cover changes in Iberian peatlands using historical data and environmental models to identify factors driving changes and conservation needs.

Triangulation reduces the polygon of error for the history of Transeurasian

The paper addresses critiques of a Transeurasian language and population history study by revising datasets and methods, showing that the original findings remain valid despite objections.

Presenting the Compendium Isotoporum Medii Aevi (CIMA) and Bayesian Case Studies

The paper introduces the CIMA isotopic dataset and applies Bayesian methods to study medieval human lifeways, animal management, and environmental conditions.

Age-Related Type I Collagen Modifications Reveal Tissue-Defining Differences Between Ligament and Tendon

This study compares collagen post-translational modifications in bovine tendons and ligaments to identify tissue-specific differences in cross-linking profiles and fibril size.

Anti-GD2 antibody disrupts GD2:Siglec-7 interactions and synergizes with CD47 blockade to mediate tumor eradication

This study shows that combining anti-GD2 and anti-CD47 antibodies enhances anti-tumor responses by recruiting macrophages and disrupting the GD2:Siglec-7 interaction in GD2+ cancers.

A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process

This paper presents a crystal structure of an immature SARS-CoV-2 main protease, revealing conformational changes that hinder dimerization and activity, and identifies potential therapeutic targets.