Author

G. Posthuma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. Klumperman· 3 shared C. de Heus· 2 shared A. Aharonov· 1 shared A. Baz Morelli· 1 shared A. Carter· 1 shared A. de Maziere· 1 shared A. Shakked· 1 shared A. Shoffner· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

J. Klumperman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bimodal Endocytic Probe for Three-Dimensional Correlative Light and Electron Microscopy

J. Fermie, L. de Jager, H. Foster, T. Veenendaal, C. de Heus, S. van Dijk, C. ten Brink, V. Oorschot, L. Yang, W. Li, W. Muller, S. Howes, A. Carter, F. Foerster, G. Posthuma, , N. Liv

This paper introduces fBSA-Au, a bimodal endocytic tracer for 2D and 3D CLEM, enabling accurate registration of fluorescence to EM data with sub-200 nm precision.

bioRxiv · May 18, 2021Cell Biology

Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

S. Nalle, R. Barreira da Silva, H. Zhang, M. Decker, C. Chalouni, M. Xu, G. Posthuma, A. de Maziere, J. Klumperman, A. Baz Morelli, S. Fleire, A. Verkman, S. Trombetta, M. Albert, I. Mellman

This study identifies aquaporin-3 as a regulator of endosome-to-cytosol transfer by facilitating hydrogen peroxide entry, which induces lipid peroxidation and antigen release.

bioRxiv · Aug 19, 2020Immunology

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

H. Honkoop, D. de Bakker, A. Aharonov, F. Kruse, A. Shakked, P. Nguyen, C. de Heus, L. Garric, M. Muraro, A. Shoffner, F. Tessadori, J. Peterson, W. Noort, G. Posthuma, D. Grun, , J. Bakkers

This study identifies a metabolic switch from OXPHOS to glycolysis in regenerating zebrafish hearts, showing it is essential for cardiomyocyte proliferation and heart regeneration.

bioRxiv · Dec 18, 2018Cell Biology