Author

G. Schenk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

N. Mitic· 3 shared B. L. Schulz· 2 shared L. W. Guddat· 2 shared L. Wilson· 2 shared M. Monteiro Pedroso· 2 shared R. P. McGeary· 2 shared A. Clark· 1 shared A. Furtado· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

N. Mitic

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms

C. Selleck, M. Monteiro Pedroso, L. Wilson, S. Krco, E. G. Knaven, M. Miraula, N. Mitic, J. Larrabee, T. Bruck, A. Clark, L. Guddat, G. Schenk

This study investigates the structure and mechanism of two marine-derived β-lactamase-lactonase enzymes, revealing their structural conservation and diverse reaction mechanisms.

Scientific Reports · Jul 30, 2020Peer-reviewedBiochemistry

Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse and widespread in the environment.

M. Monteiro Pedroso, D. Waite, O. Melse, L. Wilson, N. Mitic, R. P. McGeary, I. Antes, L. W. Guddat, P. Hugenholtz, G. Schenk

The paper identifies a broad phylogenetic diversity of B3 MBLs in environmental microbes and shows that a variant (B3-RQK) is sensitive to clavulanic acid due to a lysine residue in its active site.

Protein & Cell · Jun 15, 2020Peer-reviewedBiochemistry

Structural elements that modulate the substrate specificity of plant purple acid phosphatases: avenues for improved phosphorus acquisition in crops

D. Feder, R. P. McGeary, N. Mitic, T. Lonhienne, A. Furtado, B. L. Schulz, R. J. Henry, S. Schmidt, L. W. Guddat, G. Schenk

The paper identifies structural elements in plant purple acid phosphatases that influence substrate specificity, offering insights for improving phosphorus acquisition in crops.

bioRxiv · Aug 28, 2019Biochemistry

Global analysis of epigenetic heterogeneity identifies divergent drivers of esophageal squamous cell carcinoma

W. CAO, H. Lee, W. Wu, A. Zaman, S. McCorkle, M. Yan, J. Chen, Q. Xing, N. Sinnott-Armstrong, H. Xu, M. R. Sailani, W. Tang, Y. Cui, J. Liu, H. Guan, , T. G. Bivona

The paper identifies epigenetic drivers of esophageal squamous cell carcinoma through multi-omics analysis, revealing hypomethylation patterns and non-canonical WNT signaling activation.

bioRxiv · May 18, 2019 · PreprintCell Biology

Proteomics reveals profound metabolic changes in the alcohol use disorder brain

C. Enculescu, E. D. Kerr, B. K. Y. Yeo, P. R. Dodd, G. Schenk, M. R. S. Fortes, B. L. Schulz

The paper uses proteomics to identify metabolic changes in the brains of individuals with alcohol use disorder, revealing a shift toward acetate utilization.

bioRxiv · Oct 20, 2018Biochemistry