Author

H. Guan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:plant (other)· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2

Frequent Co-Authors

J. Wang· 3 shared W. Wu· 2 shared X. Liu· 2 shared Y. Zhou· 2 shared A. H. Shain· 1 shared A. Nurmamat· 1 shared A. Zaman· 1 shared B. Huang· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersImmunology

J. Wang

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9 papers

Recent·Most cited

Evolutionary analysis of paired box gene family and biological function exploration of Lr.Pax7 in lamprey (Lethenteron reissneri)

Y. Han, X. Liu, A. Nurmamat, Z. Yan, Y. Jiang, H. Guan, Y. Zhou, X. Min, R. Zhuang, S. Zhang, D. Li, Y. Pang, L. Zhao

This study identifies and analyzes Pax7 in lamprey, showing its potential ancestral role and functional similarities to higher vertebrates in metabolic and developmental processes.

bioRxiv · May 6, 2024 · PreprintEvolutionary Biology

Cervical collagen network porosity assessed by SHG endomicroscopy distinguishes preterm and normal pregnancy - a pilot study

W. Liang, Y. Liu, H. Guan, V. Sakulsaengprapha, K. Luby-Phelps, M. Mahendroo, X. Li

bioRxiv · Mar 12, 2024Bioengineering

Autoantibodies against eukaryotic translation elongation factor 1 delta (EEF1D) in two patients with autoimmune cerebellar ataxia

L. Guo, H. Ren, S. Fan, X. Chao, M. Liu, H. Guan, J. Wang

This study identifies anti-EEF1D autoantibodies in two patients with autoimmune cerebellar ataxia, suggesting their potential as a biomarker for diagnosis and recurrence prevention.

bioRxiv · Sep 5, 2023Immunology

Extraction, purification and anti-TMV effects of α (β)-2,7,11-cembratriene-4,6-diol from tobacco leaves

Y. Feng, H. Jia, H. Guan, W. Zhang, Y. Zhou, K. Liu, Y. Wang, Q. Li, W. Chen, M. A. Sohail, J. Wang, S. Huang, J. Wei

This study extracts and purifies β-2,7,11-cembratriene-4,6-diol from tobacco leaves and demonstrates its antiviral activity against TMV through in vivo and molecular assays.

bioRxiv · Jun 1, 2021Plant Biology

Specific and conserved patterns of microbiota-structuring by maize benzoxazinoids in the field

S. Cadot, H. Guan, M. Bigalke, J.-C. Walser, G. Jander, M. Erb, M. van der Heijden, K. Schlaeppi

This study shows that maize secretes benzoxazinoids (BXs) that shape root and rhizosphere microbiota, with BXs significantly affecting fungal communities across different soil types.

bioRxiv · May 3, 2020Plant Biology

LINCS gene expression signatures analysis revealed bosutinib as a radiosensitizer of breast cancer cells by targeting eIF4G1

S. Hu, P. Zhou, X. Liu, X. Yin, D. XIE, B. Huang, H. Guan

This study identifies bosutinib as a radiosensitizer for breast cancer by targeting eIF4G1, enhancing radiation efficacy and reducing drug dosage.

bioRxiv · Apr 24, 2020Cancer Biology

Molecular basis of ubiquitination catalyzed by the bacterial transglutaminase MavC

H. Guan, J. Fu, T. Yu, Z.-X. Wang, Z.-Q. Luo, S. Ouyang

This study determines the structure of the MavC-UBE2N-Ub complex, revealing the mechanism of MavC's transglutaminase and deamidase activities and its opposing activity to MvcA.

bioRxiv · Mar 10, 2020Microbiology

Transcriptome Analysis of xa5-mediated Resistance to Bacterial Leaf Streak in Rice (Oryza sativa L.)

X. Xie, Z. Chen, H. Guan, Y. Zheng, J. Zhang, M. Qin, W. Wu

The paper investigates the role of xa5 in BLS resistance by analyzing transcriptome changes in Xa5-RNAi rice lines compared to wild-type, finding enhanced cell death gene responses.

bioRxiv · Aug 8, 2019Plant Biology

Global analysis of epigenetic heterogeneity identifies divergent drivers of esophageal squamous cell carcinoma

W. CAO, H. Lee, W. Wu, A. Zaman, S. McCorkle, M. Yan, J. Chen, Q. Xing, N. Sinnott-Armstrong, H. Xu, M. R. Sailani, W. Tang, Y. Cui, J. Liu, H. Guan, , T. G. Bivona

The paper identifies epigenetic drivers of esophageal squamous cell carcinoma through multi-omics analysis, revealing hypomethylation patterns and non-canonical WNT signaling activation.

bioRxiv · May 18, 2019 · PreprintCell Biology