Multimodal single-cell profiling reveals cancer crosstalk between macrophages and stromal cells in poor prognostic cholangiocarcinoma patients.
L. R. Heij, S. Hayat, K. Reichel, S. Maryam, C. Rourke, X. Tan, M. van den Braber, J. Verhoeff, M. Halder, F. Peisker, G. Wiltberger, J. Bednarsch, D. Heise, J. Campello Deierl, S. Lang, , U. Neumann
This study uses multimodal single-cell profiling to identify immune cell crosstalk mechanisms in poor prognostic cholangiocarcinoma, revealing key ligand pairs and pathways contributing to immune exhaustion.
bioRxiv · Feb 3, 2024Cancer Biology