ImmunologybioRxiv
Antibody Complementarity Determining Region Design Using High-Capacity Machine Learning
G. Liu, H. Zeng, J. Mueller…·D. K. Gifford
This paper introduces a machine learning method to design human IgG antibodies with superior target affinity and specificity, using high-throughput data without requiring target structural information.
DOI 10.1093/bioinformatics/btz895