Author

I. Datta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

H. Noushmehr· 2 shared L. Poisson· 2 shared A. D. Berezovsky· 1 shared A. deCarvalho· 1 shared A. Iavarone· 1 shared A. M. E. Walenkamp· 1 shared A. Y. Taha· 1 shared B. Wang· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

H. Noushmehr

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

A. D. Berezovsky, O. Nuga, I. Datta, K. Bergman, T. Sabedot, K. Gurdziel, S. Irtenkauf, L. Hasselbach, Y. Meng, C. Mueller, E. Petricoin, S. Brown, N. Purandare, S. Aras, T. Mikkelsen, , A. deCarvalho

This study examines how genomic background and developmental state affect signaling pathways and therapy response in GBM patient-derived cells, finding that differentiation increases TMZ resistance and activates DNA-damage interferon responses.

bioRxiv · Mar 14, 2024 · PreprintCancer Biology

Blood-based targeted metabolipidomics reveals altered omega fatty acid-derived lipid mediators in relapsing-remitting multiple sclerosis patients

I. Zahoor, J. Waters, N. Ata, I. Datta, T. Pedersen, M. Cerghet, L. Poisson, S. Markovic-Plese, R. Rattan, A. Y. Taha, J. W. Newman, S. Giri

The paper identifies altered omega fatty acid-derived lipid mediators in RRMS patients using metabolipidomics, suggesting their potential as biomarkers for diagnosis and prognosis.

bioRxiv · Jan 4, 2024 · PreprintBiochemistry

Senescent cells and macrophages cooperate through a multikinase signaling network to promote intestinal transformation in Drosophila.

I. Datta, E. Bangi

bioRxiv · May 15, 2023Cancer Biology

Oligomer-to-Monomer Transition Underlies the Chaperone Function of AAGAB in AP1/AP2 Assembly

Y. Tian, I. Datta, R. Yang, C. Wan, B. Wang, H. He, S. Li, J. Shen, Q. Yin

This study identifies the dual role of AAGAB's tetramerization domain in stabilizing AAGAB and binding substrates during AP1/AP2 complex assembly.

bioRxiv · Mar 11, 2022Biochemistry

Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

F. S. Varn, K. C. Johnson, T. E. Wade, T. M. Malta, T. S. Sabedot, F. P. Barthel, H. Kim, N. Ahmed, I. Datta, J. S. Barnholtz-Sloan, S. Bakas, F. D'Angelo, H. K. Gan, L. Garofano, J. T. Huse, , The GLASS Consortium

This study analyzes longitudinal glioma data to identify recurrence-associated changes in genetics and microenvironment linked to therapy resistance.

bioRxiv · May 3, 2021Cancer Biology