Author

C. Wan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Bioengineering· 1 Biophysics· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:metagenomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. Wang· 3 shared S. Li· 2 shared A. D. Kimes· 1 shared A. Emili· 1 shared A. Grisolano· 1 shared A. J. Hemmerla· 1 shared B. D. Ulery· 1 shared B. T. Darkow· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

B. Wang

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

De-glycosylated non-structural protein 1 enhances dengue virus clearance by limiting PD-L1/PD-1 mediated T cell apoptosis

F. Hj Idris, D. H. R. Ting, E. T. X. Tan, C. Wan, K. R. Chan, P. I. Benke, J. K. Marzinek, J. M. Copping, Q. H. Li, I. Walsh, J. R. Allison, P. J. Bond, F. T. Torta, T. Nguyen-Khuong, S. ALONSO

This study shows that de-glycosylation of N207 in DENV NS1 reduces viral fitness and enhances clearance by limiting PD-L1/PD-1 mediated T cell apoptosis.

bioRxiv · Jan 8, 2024 · PreprintMicrobiology

Determining the microbial species content in tissue from Alzheimer's and Parkinson's Disease patients

R. Leitao, C. Wan, M. Fisher, J. Rhodes

This study develops a nanopore sequencing method to detect fungal DNA in brain tissue and CSF from Alzheimer's and Parkinson's Disease patients, revealing fungal presence in healthy and diseased samples.

bioRxiv · Oct 25, 2023 · PreprintMicrobiology

Spinal Fusion Properties of Mechanically-Reinforced, Osteomodulatory Chitosan Hydrogels

B. T. Darkow, J. P. Herbert, M. J. Messler, A. Grisolano, A. J. Hemmerla, A. D. Kimes, J. Lanza, Y. Sun, J. R. Crim, D. Stensby, C. Wan, D. K. Moore, B. D. Ulery

This study develops a chitosan hydrogel reinforced with cellulose and allograft to improve spinal fusion, showing enhanced compressive strength, biocompatibility, and osteoinductive properties in vitro and in vivo.

bioRxiv · May 26, 2022Bioengineering

Gene mutations and molecular evolution of the chikungunya virus E1 and E2 from 2014 to 2019

X. Li, X. Li, J. Liu, S. Liang, H. Chen, C.-W. Ke, C. Wan

This study analyzes gene mutations in CHIKV E1 and E2 proteins from 2014 to 2019, identifying common mutation sites and their potential impact on immune escape and serological detection.

bioRxiv · Mar 16, 2022 · PreprintEvolutionary Biology

Oligomer-to-Monomer Transition Underlies the Chaperone Function of AAGAB in AP1/AP2 Assembly

Y. Tian, I. Datta, R. Yang, C. Wan, B. Wang, H. He, S. Li, J. Shen, Q. Yin

This study identifies the dual role of AAGAB's tetramerization domain in stabilizing AAGAB and binding substrates during AP1/AP2 complex assembly.

bioRxiv · Mar 11, 2022Biochemistry

Data-informed discovery of hydrolytic nanozymes

S. Li, Z. Zhou, Z. Tie, B. Wang, M. Ye, L. Du, R. Cui, W. Liu, C. Wan, Q. Liu, S. Zhao, Q. Wang, Y. Zhang, S. Zhang, H. Zhang, , H. Wei

This paper develops data-informed strategies to design hydrolytic nanozymes with enhanced catalytic activity and broad substrate specificity.

bioRxiv · Dec 8, 2020Biophysics

Global Landscape of Native Protein Complexes in Synechocystis sp. PCC 6803

C. Xu, B. Wang, L. Yang, L. Z. Hu, L. Yi, Y. Wang, S. Chen, A. Emili, C. Wan

The paper identifies 291 protein complexes and 24,092 PPIs in Synechocystis sp. PCC 6803, revealing functional roles of previously uncharacterized proteins and their interactions across biological processes.

bioRxiv · Mar 7, 2020Biochemistry

Evaluation of Postharvest Storability of Ponkan Mandarins at Different Storage Temperatures Based on Principal Component Analysis

N. Cai, c. wan, J. Chen, C. Chen

This study evaluates the optimal storage temperature for Ponkan mandarins using PCA, finding that 10°C best preserves quality and reduces oxidative stress.

bioRxiv · Nov 13, 2019 · PreprintPlant Biology