Author

I. Hatin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Assay:DNA methylation· 1

Frequent Co-Authors

O. NAMY· 4 shared A. Babosan· 1 shared A. Carvalho· 1 shared A. K. Dube· 1 shared A. Lopes· 1 shared A. Moris· 1 shared A. Samri· 1 shared B. Autran· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersMicrobiology

O. NAMY

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Author profile →

4 papers

Recent·Most cited

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

L. Fruchard, A. Babosan, A. Carvalho, M. Lang, B. Li, M. Duchateau, Q. Giai Gianetto, M. Matondo, F. Bonhomme, I. Hatin, H. Arbes, C. Fabret, E. Corler, G. Sanchez, V. MArchand, , Z. Baharoglu

This study shows that Q34 modification in tRNA affects translational efficiency in Vibrio cholerae under aminoglycoside stress, leading to reprogramming of gene expression and antibiotic tolerance.

bioRxiv · Sep 26, 2022Microbiology

Extensive uORF translation from HIV-1 transcripts conditions DDX3 dependency for expression of main ORFs and elicits specific T cell immune responses in infected individuals

E. Labaronne, D. Decimo, L. Bertrand, L. Guiguettaz, T. J. Sohier, D. Cluet, V. Vivet-Boubou, C. Dahoui, P. Francois, I. Hatin, O. Lambotte, A. Samri, B. Autran, L. Etienne, C. Goujon, , E. Ricci

The paper characterizes HIV-1 translational landscape, revealing uORF translation and its role in DDX3 dependency and T cell immune responses.

bioRxiv · Apr 29, 2022Microbiology

Intergenic ORFs as elementary structural modules of de novo gene birth and protein evolution

C. Papadopoulos, I. Callebaut, J.-C. Gelly, I. Hatin, O. Namy, M. Renard, O. Lespinet, A. Lopes

This study explores how noncoding sequences in yeast can generate structural protein diversity and contribute to de novo gene birth.

bioRxiv · Apr 13, 2021Evolutionary Biology

The high turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations

E. Durand, I. Gagnon-Arsenault, J. Hallin, I. Hatin, A. K. Dube, L. Nielly-Thibault, O. Namy, C. R. Landry

The paper examines de novo ORF emergence in wild yeast, finding some intergenic ORFs show gene-like characteristics despite lower translation efficiency and suggesting functional innovation potential.

bioRxiv · Dec 21, 2018Evolutionary Biology