M. Lang

Assembling a true "Olympic Gel" from >16,000 combinatorial DNA rings

This paper creates a true Olympic gel from over 16,000 DNA rings, showing unique mechanical properties and swelling behavior due to entanglements.

Genome-wide sweeps create fundamental ecological units in the human gut microbiome

The paper identifies genome-wide selective sweeps in the human gut microbiome, revealing ecologically distinct populations linked to age and colorectal cancer.

Performance effects from different shutdown methods of three electrode materials for the power-to-gas application with electromethanogenesis

This study evaluates the performance of three electrode materials during shutdowns in microbial electrochemical systems for electromethanogenesis, finding that nickel cathodes show the fastest recovery.

FrameDiPT: SE(3) Diffusion Model for Protein Structure Inpainting

FrameDiPT is a diffusion model for protein structure inpainting that recovers masked sections using sequence and structural context, achieving comparable accuracy to existing models with limited data.

The Auxin Response Factor ARF27 is required for maize root morphogenesis

This study identifies ARF27 as a key regulator of auxin-mediated root morphogenesis in maize, showing its role in root hair formation and auxin response.

Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters

This study identifies uridine as a molecule that enhances aminoglycoside uptake in Gram-negative bacteria by activating carbohydrate transporters, improving antibiotic efficacy against resistant strains.

Identification of the active mechanism of aminoglycoside entry in V. cholerae through characterization of sRNA ctrR, regulating carbohydrate utilization and transport.

This paper identifies the active transport mechanism of aminoglycosides in V. cholerae by characterizing the sRNA ctrR, which regulates carbohydrate utilization and transport.

RavA-ViaA links Vibrio cholerae Cpx and Zra2 envelope stress to antibiotic response

This study shows that deletion of the ravA-viaA operon in Vibrio cholerae increases tolerance to aminoglycosides and affects polymyxin B sensitivity and vancomycin resistance by modulating Cpx and Zra2 two-component systems.

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

This study shows that Q34 modification in tRNA affects translational efficiency in Vibrio cholerae under aminoglycoside stress, leading to reprogramming of gene expression and antibiotic tolerance.

No evidence for asymmetric sperm deposition in a species with asymmetric male genitalia

The study investigates whether asymmetric male genitalia in Drosophila pachea lead to differential sperm allocation in female storage organs, but finds no evidence for asymmetric sperm deposition.

Evolution of a novel left-right asymmetry in organ size by co-option of a tissue rotation process

The paper shows how a novel left-right asymmetry in Drosophila pachea genitalia evolved through co-option of a tissue rotation process, with asymmetry direction determined by rotation direction.

Long-term forest monitoring unravels constant mortality rise in European forests

The paper analyzes long-term forest mortality trends in Europe, finding a significant increase in tree mortality rates linked to decreasing soil moisture and drought conditions over the past 25 years.

European-wide forest monitoring substantiate the neccessity for a joint conservation strategy to rescue European ash species (Fraxinus spp.)

The paper analyzes European ash tree decline due to ash dieback, finding increased defoliation and mortality over three decades, with urgent calls for pan-European conservation strategies.

Male genital lobe morphology affects the chance to copulate in Drosophila pachea

This study shows that male genital lobe length in Drosophila pachea influences copulation initiation but not sperm transfer.

Widespread introgression across a phylogeny of 155 Drosophila genomes

The paper analyzes 155 Drosophila genomes to detect widespread introgression across nine monophyletic radiations, revealing both ancient and recent hybridization events.

Sleeping ribosomes: bacterial signaling triggers RaiA mediated persistence to aminoglycosides.

The paper shows indole, induced by sublethal tobramycin, increases persistence to aminoglycosides in V. cholerae via RaiA-mediated ribosome storage.

Salicylate, Bile Acids and Extreme Acid Cause Fitness Tradeoffs for Multidrug Pumps in Escherichia coli K-12

This study investigates how salicylate, bile acids, and extreme acid affect the fitness of multidrug efflux pumps in E. coli, revealing tradeoffs and conditions under which these pumps confer advantages or costs.

Population dynamics of decision making in temperate bacteriophages

The paper develops a stochastic model to study how temperate bacteriophages make decisions between lysis and lysogeny during coinfections, finding that coinfections provide limited population-level information but can offer competitive advantages.

Repeated evolution of asymmetric genitalia and right-sided mating behavior in the Drosophila nannoptera species group

The paper examines the evolution of genital asymmetry and mating behavior in Drosophila nannoptera group species, finding repeated evolution of asymmetric genitalia and right-sided mating in some species.

Correlated Evolution of two Sensory Organs via a Single Cis-Regulatory Nucleotide Change

A single nucleotide change in a gene regulatory region contributes to evolutionary changes in two distinct organs in Drosophila.

Evolution of sexually-transferred steroids in Anopheles mosquitoes

The paper analyzes the evolution of sexually-transferred steroids in Anopheles mosquitoes and finds that male steroid production and transfer are specific to the Cellia subgenus and not correlated with malaria transmission.