Author

J. Ayala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Qu· 1 shared D. J. Fulton· 1 shared E. Li· 1 shared G. Beggs· 1 shared G. Hooks· 1 shared H. Su· 1 shared J. Li· 1 shared J. Liu· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPathology

C. Qu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy

W. Wang, E. Li, J. Zou, C. Qu, J. Ayala, Y. Wen, M. S. Islam, N. L. Weintraub, D. J. Fulton, Q. Liang, J. Zhou, J. Liu, J. Li, Y. Sun, H. Su

This study identifies RBX2 as a key component of the CRL5 ubiquitin ligase that regulates mitophagy in cardiomyocytes independently of PARKIN, maintaining cardiac homeostasis.

bioRxiv · Feb 24, 2024Pathology

Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

G. Hooks, J. Ayala, G. Beggs, J. R. Perfect, M. Schumacher, W. M. Shafer, R. G. Brennan

This study identifies hormonal steroids that bind MtrR, a regulator in Neisseria gonorrhoeae, leading to reduced DNA binding and activation of multidrug efflux pumps and stress-response mechanisms.

bioRxiv · Jun 13, 2023 · PreprintBiochemistry