Author

J. Barbier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

D. Gillet· 3 shared A. Alloatti· 1 shared A. Bonaud· 1 shared A. Forrester· 1 shared A. Goldar· 1 shared A. Machelart· 1 shared A. Mettouchi· 1 shared A. Peden· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

D. Gillet

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Selective inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation

N. He, L. Depta, C. Rossetti, M. Cigler, M. Michon, O. R. Dan, J. G. F. Hoock, J. Barbier, D. Gillet, A. Forrester, G. E. Winter, L. Laraia

This study identifies oxybipins, selective OSBP inhibitors, which block retrograde trafficking and reduce Shiga toxin toxicity by inducing Golgi degradation.

bioRxiv · Apr 1, 2023 · PreprintCell Biology

Plasma cell maintenance and antibody secretion are under the control of Sec22b-mediated regulation of organelle dynamics

A. Bonaud, L. Gargowitsch, S. Gilbert, E. Rajan, P. Canales-Herrerias, D. Stockholm, N. Rahman, M. Collins, D. L. Hill, A. Alloatti, N. Alouche, S. Balor, V. Soldan, D. Gillet, J. Barbier, , M. Espeli

This study identifies Sec22b as a critical regulator of plasma cell maintenance and function by controlling organelle dynamics, leading to reduced antibody secretion and impaired immune response.

bioRxiv · Jan 14, 2022 · PreprintImmunology

Neural network and kinetic modelling of human genome replication reveal replication origin locations and strengths

J.-M. Arbona, H. Kabalane, J. Barbier, A. Goldar, O. Hyrien, B. Audit

The paper uses neural networks and kinetic modeling to infer replication origin locations and strengths from replication timing and direction data, revealing that origin efficiency is determined by both licensing and firing steps.

bioRxiv · Dec 15, 2021Biophysics

A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2

Y. Wu, N. Mahtal, L. Swistak, S. Sagadiev, M. Acharya, C. Demeret, S. Van der Werf, F. Guivel-Benhassine, O. Schwartz, S. Petracchini, A. Mettouchi, E. Paillares, L. Caramelle, P. Couvineau, R. Thai, , E. Lemichez

bioRxiv · Aug 13, 2021Microbiology

PAF1 facilitates RNA polymerase II ubiquitination by the Elongin A complex through phosphorylation by CDK12

G. Sanchez, J. Barbier, C. Elie, R. Kiernan, S. Rouquier

The paper shows PAF1 interacts with Elongin A to ubiquitinate RNA polymerase II, dependent on CDK12-mediated Ser2 phosphorylation of the CTD.

bioRxiv · Sep 17, 2020 · PreprintCell Biology