Author

J. Garhyan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

A. A. Pohane· 1 shared A. Balaji· 1 shared A. Beck· 1 shared A. Drelich· 1 shared A. E. S. Barentine· 1 shared A. R. Roy· 1 shared A. Rustagi· 1 shared B. M. Swarts· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. A. Pohane

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles

L. Andronov, M. Han, Y. Zhu, A. Balaji, A. R. Roy, A. E. S. Barentine, P. Patel, J. Garhyan, L. S. Qi, W. E. Moerner

This study uses super-resolution microscopy to reveal the nanoscale organization of SARS-CoV-2 replication organelles, showing distinct vgRNA and dsRNA clusters and changes over infection stages.

bioRxiv · Nov 7, 2023Microbiology

Design of SARS-CoV-2 protease inhibitors with improved affinity and reduced sensitivity to mutations

M. Westberg, Y. Su, X. Zou, P. Huang, A. Rustagi, J. Garhyan, P. B. Patel, D. Fernandez, Y. Wu, L. Ning, A. Beck, M. Karim, C. Hao, P. Saenkham-Huntsinger, V. Tat, , M. Z. Lin

This study designs a SARS-CoV-2 protease inhibitor with improved affinity and reduced mutation sensitivity compared to existing drugs.

bioRxiv · Jul 19, 2023 · PreprintMicrobiology

Trehalose recycling promotes energy-efficient mycomembrane reorganization in nutrient-limited mycobacteria

A. A. Pohane, C. R. Carr, J. Garhyan, B. M. Swarts, M. S. Siegrist

This study shows that trehalose recycling reduces energy costs for mycomembrane remodeling in nutrient-starved mycobacteria, enhancing survival under stress.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology