Author

J. Hosten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

K. Roy· 3 shared A. Beach· 2 shared B. Pandey· 2 shared C. Smith· 2 shared M. C. Keenum· 2 shared P. Pradhan· 2 shared R. Jain· 2 shared A. C. Jimenez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBioengineering

K. Roy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice

B. Pandey, Z. Wang, A. Jimenez, E. Bhatia, R. Jain, A. Beach, D. Maniar, J. Hosten, L. O'Farrell, C. Vantucci, D. Hur, R. K. Noel, R. M. Ringquist, C. Smith, M. A. Ochoa, K. Roy

This study develops a mucosal nanovaccine that enhances both systemic and lung-specific immunity against SARS-CoV-2 in mice through intranasal and intramuscular delivery.

bioRxiv · May 5, 2023 · PreprintBioengineering

Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine

A. M. Atalis, M. C. Keenum, B. Pandey, A. Beach, P. Pradhan, C. E. Vantucci, R. Jain, J. Hosten, C. Smith, L. L. Kramer, A. C. Jimenez, M. A. Armenta-Ochoa, D. A. Frey, K. Roy

This study shows that nanoparticle-delivered TLR4 and RIG-I agonists enhance immune responses to a SARS-CoV-2 subunit vaccine in mice, with route-specific effects on T and B cell responses.

bioRxiv · Jan 31, 2022Immunology

TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells in vitro and generate unique cellular immune responses in influenza vaccination

R. Toy, M. C. Keenum, P. Pradhan, K. Phang, P. Chen, C. Chukwu, A. Nguyen, J. Liu, S. Jain, G. Kozlowski, J. Hosten, M. Suthar, K. Roy

This paper shows that combining TLR7 and RIG-I adjuvants in nanoparticles enhances dendritic cell responses and improves cellular immunity in influenza vaccination.

bioRxiv · Jul 17, 2020Bioengineering