Author

J. Oki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

J. Carlson-Stevermer· 3 shared K. Holden· 3 shared A. Mac Kain· 2 shared M. Vignuzzi· 2 shared Q. D. Tran· 2 shared A. Baidaliuk· 1 shared A. Hardy· 1 shared A. J. Samelson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

J. Carlson-Stevermer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification of DAXX As A Restriction Factor Of SARS-CoV-2 Through A CRISPR/Cas9 Screen

A. Mac Kain, G. Maarifi, S.-M. Aicher, N. Arhel, A. Baidaliuk, S. Munier, F. Donati, T. Vallet, Q. D. Tran, A. Hardy, M. Chazal, F. Porrot, M. Ohainle, J. Carlson-Stevermer, J. Oki, , F. Roesch

The paper identifies DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen, showing it limits viral replication independently of SUMOylation.

bioRxiv · May 6, 2021Microbiology

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

A. J. Samelson, Q. D. Tran, R. Robinot, L. Carrau, V. V. Rezelj, A. Mac Kain, M. Chen, G. N. Ramadoss, X. Guo, S. A. Lim, I. Lui, J. Nunez, S. J. Rockwood, J. Wang, N. Liu, , M. Kampmann

This study identifies BRD2 as a regulator of ACE2 transcription and shows that BRD2 inhibitors block SARS-CoV-2 infection in human cells and animal models.

bioRxiv · Jan 19, 2021Cell Biology

Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses

R. Wang, C. R. Simoneau, J. Kulsuptrakul, M. Bouhaddou, K. Travisano, J. M. Hayashi, J. Carlson-Stevermer, J. Oki, K. Holden, N. J. Krogan, M. Ott, A. S. Puschnik

The paper identifies host factors and pathways common to SARS-CoV-2 and common cold coronaviruses using CRISPR screens, revealing shared and unique factors that support viral infection.

bioRxiv · Sep 24, 2020Microbiology