Pharmacology & ToxicologybioRxivPreprint
Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2
DOI 10.1101/2021.03.23.436648
Author
V. V. Rezelj
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2019-2021 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- BiochemistrybioRxiv
Host PDZ-containing proteins targeted by SARS-Cov-2
C. Caillet-Saguy, F. Durbesson, V. V. REZELJ…·N. Wolff
The paper identifies sixteen human PDZ binders of SARS-CoV-2 proteins E, 3a, and N, showing significant interactions and potential roles in viral replication and immune evasion.
DOI 10.1111/febs.15881 - Cell BiologybioRxiv
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
A. J. Samelson, Q. D. Tran, R. Robinot…·M. Kampmann
This study identifies BRD2 as a regulator of ACE2 transcription and shows that BRD2 inhibitors block SARS-CoV-2 infection in human cells and animal models.
- BiochemistrybioRxiv
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
M. Schoof, B. Faust, R. A. Saunders…·Barile-H
This paper develops a potent synthetic nanobody that neutralizes SARS-CoV-2 by locking its Spike protein in an inactive conformation, enabling aerosol delivery as a prophylactic or therapeutic agent.
DOI 10.1126/science.abe3255 - MicrobiologybioRxivPreprint
Modeling cell infection via virus-producing cells rather than free infectious virus significantly improves fits of an in vitro viral kinetic data
V. Bernhauerova, V. V. Rezelj, L. I. Laura, M. Vignuzzi
This study improves viral kinetic modeling by showing that cell-to-cell transmission, not free virus, better explains chikungunya and Zika virus in vitro infection dynamics.
DOI 10.1101/627968