J.-H. Kim

Serum Lipidome Profiling Reveals a Distinct Signature of Ovarian Cancer in Korean Women

This study identifies a distinct lipidome signature in Korean women with ovarian cancer, showing early-stage alterations and a predictive panel of 17 lipids with 85% accuracy.

Optimization of Shoot Regeneration and Application of CRISPR/Cas9 Gene Editing to Cultivated Strawberry

This study optimizes shoot regeneration in strawberry cultivars and applies CRISPR/Cas9 to edit the FaPDS gene, achieving high regeneration and mutation rates.

Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to vaccination

The paper develops a method to recover full-length BCR sequences from single-cell RNA libraries and applies it to study convergent B cell responses to vaccination in rhesus macaques.

Trogocytic-molting of T-cell microvilli controls T-cell clonal expansion

The paper identifies trogocytic-molting as a process where T cells release TCRs via microvilli, leading to increased surface TCRs and metabolic reprogramming to support clonal expansion.

Adolescent parvalbumin expression in the left orbitofrontal cortex shapes sociability in female mice

This study shows that adolescent social isolation in female mice leads to increased sociability, reduced parvalbumin expression, and decreased social sniffing activity in the left orbitofrontal cortex, highlighting the role of PV+ inhibitory circuits in shaping female social behavior.

Efficacy and gut dysbiosis of gentamicin-intercalated smectite as a new therapeutic agent against Helicobacter pylori in a mouse model

This paper evaluates a new gentamicin-intercalated smectite (S-GM) therapy for H. pylori in mice, showing comparable efficacy to standard triple therapy and reduced gut dysbiosis.

Marine deforestation leads to widespread loss of ecosystem function

The paper shows that marine deforestation in the Aleutian Archipelago reduces biodiversity and primary productivity across 1000 km of coastline.

Mul1 suppresses Nlrp3 inflammasome activation through ubiquitination and degradation of Asc

This study shows that Mul1 suppresses Nlrp3 inflammasome activation by ubiquitinating and degrading Asc, thereby preventing excessive inflammation.

Electrostatic-assemblies of single-walled carbon nanotubes and sequence-tunable peptoid polymers detect a lectin protein and its target sugars

This paper develops synthetic nanosensors using peptoid polymers on SWNTs to detect lectin proteins and their target sugars with high sensitivity and stability.

Unique unfoldase/aggregase activity of a molecular chaperone that dysregulates a translational elongation factor

This study shows Hsp33's non-canonical unfoldase/aggregase activity causes EF-Tu aggregation and degradation under heat stress, impacting cell survival.

Development of three-dimensional articular cartilage construct using silica nano-patterned substrate

This study develops a 3D spheroid culture system using silica nano-patterned substrates to enhance the chondrogenic differentiation of fetal cartilage-derived progenitor cells.

Comparative transcriptome analysis reveals higher expression of stress and defense responsive genes in dwarf soybeans obtained from the crossing of G. max and G. soja

The paper compares transcriptomes of normal and dwarf soybeans to identify differentially expressed genes related to stress, defense, and growth.

Growth hormone transgenesis disrupts immune function in muscle of coho salmon (Oncorhynchus kisutch) impacting cross-talk with growth systems

This study shows that GH transgenesis in coho salmon disrupts immune function and growth-immune cross-talk in muscle, with implications for farmed salmon health.