Author

J.-R. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:non-human primate· 1

Frequent Co-Authors

J. Wang· 2 shared M. Ding· 2 shared Q. Jin· 2 shared X. Tian· 2 shared A. Domenech· 1 shared C. Gallay· 1 shared D. E. Briles· 1 shared H. An· 1 shared

Activity by Year

2016-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

J. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivAug 23, 2022

Pathogen Clearance-based Correlates of Immunoprotection Reveal Insightful Features of Vaccine Immunity

X. Tian, J. Wang, H. Chen…·J.-R. Zhang

This paper introduces a new vaccine evaluation system based on pathogen clearance and liver trapping to assess immunoprotective potential against bacterial infections.

DOI 10.1016/j.vaccine.2024.01.018

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivJul 19, 2022

Potent Bacterial Vaccines Require FcγRIIB-mediated Pathogen Capture by Liver Sinusoidal Endothelium

J. Wang, H. An, M. Ding…·J.-R. Zhang

This paper identifies FcγRIIB-mediated capture of antibody-coated bacteria by liver sinusoidal endothelial cells as a mechanism for superior vaccine efficacy.

DOI 10.1126/scitranslmed.ade0054

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivNov 17, 2016

High-throughput CRISPRi phenotyping in Streptococcus pneumoniae identifies new essential genes involved in cell wall synthesis and competence development

X. Liu, C. Gallay, M. Kjos…·J.-W. Veening

This study uses CRISPRi to identify essential genes in S. pneumoniae, revealing roles in cell wall synthesis and competence development, and highlights potential antibiotic targets.

DOI 10.15252/msb.20167449

non-human primategenetic perturbation / CRISPR

𝕏 PostBluesky