PhysiologybioRxivPreprint
Lithocholic acid targets TULP3 to activate sirtuins and AMPK to retard ageing
Q. Qu, Y. Chen, Y. Wang…·Y. Yu
This study identifies LCA's mechanism of action through TULP3-sirtuin-v-ATPase-AMPK pathway to activate AMPK and extend lifespan in model organisms.
DOI 10.1101/2023.12.07.570558