K. Chattopadhyay

This study shows that Zn-dependent structural changes in SOD1 affect its ability to undergo liquid-liquid phase separation, which may contribute to ALS pathology.

This study shows A{beta}-40 induces myelin membrane tubulation in vitro through binding and aggregation, revealing mechanisms of potential neuronal demyelination in Alzheimer's Disease.

This study shows that Zn absence, not Cu, affects SOD1 membrane attachment and aggregation in an ALS model, linking it to disease progression.

The paper shows lipid droplets promote Ago2 phase separation, reduce Dicer1 levels, and decrease miR-122 activity in hepatic cells under lipotoxic stress.

The paper investigates how membrane composition and lipid-to-protein ratio affect the aggregation kinetics of yeast prion protein Sup35, finding biphasic aggregation at optimal lipid concentrations.

The paper analyzes the SARS-CoV-2 spike RBD using evolutionary and structural methods to identify potential druggable regions.

This study shows that the Leishmania Donovani protein KMP-11 induces membrane phase transition in macrophages, facilitating infection by altering membrane tension and lipid raft structure.

The paper identifies QTLs associated with grain yield and related traits in rice using SSR markers and association analysis.

This study shows heme reduces alpha-Synuclein toxicity by altering its oligomer structure, preventing harmful fibril formation.

The paper investigates how small molecules affect the conformational dynamics and aggregation of alpha synuclein, showing additive effects of an inhibitor and facilitator on different stages of aggregation.