K. Ono

PRDX6 dictates ferroptosis sensitivity by directing cellular selenium mobilization

The paper shows PRDX6 influences ferroptosis sensitivity by managing cellular selenium levels, which affects GPX4 function.

A novel VCP modulator, KUS121, attenuates atherosclerosis progression by maintaining intracellular ATP and mitigating ER stress in endothelial cells

This study shows that KUS121 reduces atherosclerosis by maintaining ATP levels and reducing ER stress in endothelial cells.

A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice

The paper investigates the effects of a Neanderthal/Denisovan GLI3 variant in mice, finding it alters skeletal morphology without affecting protein stability or activator-dependent transcription.

Testing the Tea Bag Index as a potential indicator for assessing litter decomposition in aquatic ecosystems

The paper validates the Tea Bag Index method in aquatic ecosystems and finds it inaccurate due to non-plateauing decomposition and model discrepancies.

Shaping sustainable harvest boundaries for marine populations despite estimation bias

This paper develops a method to optimize harvest control rules for marine populations despite estimation bias, showing that accounting for biases can reduce overharvest risk and stabilize catch limits.

Two Caenorhabditis elegans calponin-related proteins have overlapping functions to maintain cytoskeletal integrity and are essential for reproduction

This study identifies overlapping and distinct functions of two calponin-related proteins in C. elegans, showing they maintain cytoskeletal integrity and are essential for reproduction.

Association between Japanese community health workers willingness to continue service and two categories of motives: altruistic and self-oriented

This study examines how altruistic and self-oriented motives influence Japanese community health workers' willingness to continue service, finding both motives positively affect retention with altruistic motives having a slightly stronger effect.