Author

Y.-B. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. A. Hakimi· 2 shared C.-H. Lee· 2 shared E. Reznik· 2 shared J. Coleman· 2 shared M. I. Carlo· 2 shared M. Zucker· 2 shared P. Russo· 2 shared R. R. Kotecha· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. A. Hakimi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular Characterization of the Tumor Microenvironment in Renal Medullary Carcinoma

D. S. Tourigny, M. Zucker, M. Kim, P. Russo, J. Coleman, C.-H. Lee, M. I. Carlo, Y.-B. Chen, A. A. Hakimi, R. R. Kotecha, E. Reznik

This study characterizes the tumor microenvironment of renal medullary carcinoma using genomic, metabolic, and single-cell RNA-sequencing data, identifying key molecular features and potential therapeutic targets.

bioRxiv · Apr 28, 2022 · PreprintCancer Biology

Genomic and Metabolic Hallmarks of SDH- and FH-Deficient Renal Cell Carcinomas

A. Yoo, C. Tang, M. Zucker, K. Fitzgerald, P. M. Rappold, K. Weiss, B. Freeman, C.-H. Lee, N. Schultz, R. Motzer, P. Russo, J. Coleman, V. E. Reuter, Y.-B. Chen, M. I. Carlo, , E. Reznik

This study compares the genomic and metabolic features of SDH- and FH-deficient renal cell carcinomas, identifying distinct genetic and metabolic abnormalities.

bioRxiv · Jun 9, 2021Cancer Biology

Variation in the life history strategy of cells underlies tumor’s functional diversity

X. Lu, T. Li, J. Liu, J. Feng, Z. Liu, S. Liu, M. Zhang, Y. Zhang, Y. Hou, D. Wu, C. Li, Y.-B. Chen, C.-I. Wu, H. Chen

This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.

bioRxiv · Nov 4, 2019 · PreprintEvolutionary Biology

Convergent genomic signatures of high altitude adaptation among domestic mammals

D.-D. Wu, C.-P. Yang, M.-S. Wang, K.-Z. Dong, D.-W. Yan, Z. Hao, S.-Q. Fan, S.-Z. Chu, Q.-S. Shen, L.-P. Jiang, Y. Li, L. Zeng, H. Liu, H.-B. Xie, Y.-F. Ma, , Y.-p. Zhang

This study identifies convergent genomic signatures of high altitude adaptation in domestic mammals by analyzing 327 genomes, revealing positive selection in genes like EPAS1 and C10orf67.

bioRxiv · Aug 22, 2019Evolutionary Biology