Author

K.-H. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Assay:imaging· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Organism:rat· 2

Frequent Co-Authors

J. Cao· 4 shared Z. Liu· 4 shared F. Wiede· 2 shared P. Beavis· 2 shared T. L. Powley· 2 shared T. Tiganis· 2 shared X. Du· 2 shared C. Kearny· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersBioengineering

J. Cao

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

F. Wiede, K.-H. Lu, X. Du, M. Zessig, R. Xu, P. K. Goh, C. Xirouchaki, S. Hogarth, S. Greatorex, K. Sek, R. Daly, P. Beavis, P. Darcy, N. Tonks, T. Tiganis

This study identifies PTP1B as an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity, showing its deletion or inhibition enhances tumor suppression.

bioRxiv · Nov 11, 2021Cancer Biology

Automatic Assessment of Human Gastric Motility and Emptying from Dynamic 3D Magnetic Resonance Imaging

K.-H. Lu, Z. Liu, D. Jaffey, J. Wo, K. Mosier, J. Cao, X. Wang, T. L. Powley

This paper introduces an automated pipeline for analyzing dynamic 3D MRI data to assess gastric motility and emptying in healthy humans.

bioRxiv · Dec 11, 2020Bioengineering

PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours

F. Wiede, K.-H. Lu, X. Du, S. Liang, K. Hochheiser, G. Dodd, P. Goh, C. Kearny, D. Meyran, P. Beavis, M. Henderson, S. L. Park, J. Waithman, S. Zhang, Z.-Y. Zhang, , T. Tiganis

This study shows that deleting PTPN2 in T cells improves anti-tumour immunity and CAR T cell effectiveness against solid tumours.

bioRxiv · Sep 5, 2019Immunology

MRI Powered and Triggered Current Stimulator for Concurrent Stimulation and MRI

R. Mandal, N. B. Babaria, J. Cao, K.-H. Lu, Z. Liu

This paper introduces a device that provides current stimulation during MRI, powered by MRI gradient fields, and shows it can power stimulation with minimal impact on image quality.

bioRxiv · Jul 26, 2019 · PreprintBioengineering

Differential Effects of Afferent and Efferent Vagus Nerve Stimulation on Gastric Motility Assessed with Magnetic Resonance Imaging

K.-H. Lu, J. Cao, R. Phillips, T. Powley, Z. Liu

This study compares the effects of afferent and efferent vagus nerve stimulation on gastric motility using MRI in anesthetized rats, finding afferent stimulation more effective.

bioRxiv · May 25, 2019Bioengineering

Vagus Nerve Stimulation Promotes Gastric Emptying by Increasing Pyloric Opening Measured with Magnetic Resonance Imaging

K.-H. Lu, J. Cao, S. Oleson, M. P. Ward, T. L. Powley, Z. Liu

This study shows that vagus nerve stimulation increases gastric emptying in rats by relaxing the pyloric sphincter, measured using MRI.

bioRxiv · Jan 25, 2018Bioengineering