Author

L. Lantier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 5

Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:metabolism & bioenergetics· 4 Assay:bulk RNA-seq· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. K. Kim· 2 shared O. P. McGuinness· 2 shared A. H. Hasty· 1 shared A. S. Banks· 1 shared B. D. Hopkins· 1 shared B. Li· 1 shared B. N. Finck· 1 shared C. C. Hughey· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPhysiology

J. K. Kim

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5 papers

Recent·Most cited

Insulin at the Intersection of Thermoregulation and Glucose Homeostasis

N. C. Winn, M. W. Schleh, J. N. Garcia, L. Lantier, O. P. McGuinness, J. A. Blair, A. H. Hasty, D. H. Wasserman

This study shows that thermoneutral temperature reduces energy expenditure and insulin-mediated glucose fluxes in mice, while insulin-independent glucose uptake in brown fat adjusts to temperature changes without compromising glucose homeostasis.

bioRxiv · Nov 17, 2023Physiology

Disruption of Hepatic Mitochondrial Pyruvate and Amino Acid Metabolism Impairs Gluconeogenesis and Endurance Exercise Capacity in Mice

M. R. Martino, M. Habibi, D. Ferguson, R. T. Brookheart, J. P. Thyfault, G. Meyer, L. Lantier, C. C. Hughey, B. N. Finck

bioRxiv · Aug 22, 2023Physiology

Epinephrine inhibits PI3K alpha via the Hippo kinases.

T.-Y. Lin, S. Ramsamooj, K. Liberatore, L. Lantier, N. Vasan, K. Karukurichi, S.-K. Hwang, E. A. Kesicki, E. R. Kastenhuber, T. Wiederhold, T. M. Yaron, M. Zhu, Y. Ma, M. N. Paddock, G. Zhang, , M. D. Goncalves

The paper identifies Hippo kinases as inhibitors of PI3K alpha, showing epinephrine activates these kinases to suppress insulin signaling and glucose metabolism.

bioRxiv · Jul 19, 2022 · PreprintPhysiology

A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

J. K. Corrigan, D. Ramachandran, Y. He, C. Palmer, M. J. Jurczak, B. Li, R. H. Friedline, J. K. Kim, J. J. Ramsey, L. Lantier, O. P. McGuinness, A. S. Banks, Mouse Metabolic Phenotyping Center Energy Balance Working Group

This study analyzes indirect calorimetry data from thousands of mice to identify sources of metabolic variation and provides guidelines for designing and reporting metabolic experiments.

bioRxiv · Nov 12, 2019Physiology

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Humans and Mice

N. Ehrhardt, J. Cui, S. Dagdeviren, S. Saengnipanthkul, H. S. Goodridge, J. K. Kim, L. Lantier, X. Guo, Y.-D. I. Chen, L. J. Raffel, T. A. Buchanan, W. A. Hsueh, J. I. Rotter, M. O. Goodarzi, M. Peterfy

This study shows aging impairs insulin sensitivity independently of adiposity in mice and humans, suggesting distinct mechanisms from obesity-related insulin resistance.

bioRxiv · May 30, 2018Physiology