Author

L. Shaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Cancer Biology· 1 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

F. Balloux· 2 shared A. L. R. Ribeiro· 1 shared A. P. Levine· 1 shared A. P. Roberts· 1 shared A. Rieux· 1 shared A. Smith· 1 shared A. T. Brunetto· 1 shared A. Thomaz· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

F. Balloux

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance

L. O. Ogunlana, L. Shaw, D. Kuar, P. Jangir, T. Walsh, S. Uphoff, C. MacLean

This study shows how regulatory evolution and horizontal gene transfer stabilize mcr-1 resistance in E. coli despite fitness costs.

bioRxiv · Nov 4, 2022 · PreprintEvolutionary Biology

Facilitation between ecosystem engineers, salt marsh grass and mussels, produces pattern formation on salt marsh shorelines

R. Lipcius, D. G. Matthews, L. Shaw, J. Shi, S. Zaytseva

The paper shows that facilitation between salt marsh grass and mussels creates spatial patterns on salt marsh shorelines.

bioRxiv · Apr 14, 2021 · PreprintEcology

Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291

D. Zhu, H. M. L. W. Patabendige, B. R. Tomlinson, S. Wang, D. Flores, Y. He, L. Shaw, X. Sun

This study identifies Cwl0971 as a peptidoglycan hydrolase in C. difficile that affects autolysis, toxin release, sporulation, and pathogenicity.

bioRxiv · Nov 29, 2020Microbiology

Laminin N-terminus α31 regulates keratinocyte adhesion and migration through modifying the organisation and proteolytic processing of laminin 332.

L. D. Troughton, V. Iorio, L. Shaw, C. J. Sugden, K. Yamamoto, K. J. Hamill

This study shows LaNt 31 regulates keratinocyte adhesion and migration by altering laminin 332 organization and proteolytic processing.

bioRxiv · Jul 28, 2020 · PreprintCell Biology

Expression and Pharmacological Inhibition of TrkB and EGFR in Glioblastoma

K. d. V. Pinheiro, A. Thomaz, B. K. Souza, V. A. Metcalfe, N. H. Freire, A. T. Brunetto, C. B. de Farias, M. Jaeger, V. Bambini, C. G. S. Smith, L. Shaw, R. Roesler

This study examines the expression and combined inhibition of TrkB and EGFR in glioblastoma, finding enhanced anti-tumor effects in cell cultures but limited impact in mouse models.

bioRxiv · Feb 3, 2020Cancer Biology

The global distribution and spread of the mobilized colistin resistance gene mcr-1

R. Wang, L. van Dorp, L. Shaw, P. Bradley, Q. Wang, X. Wang, L. Jin, Q. Zhang, Y. Liu, A. Rieux, T. Dorai-Schneiders, L. A. Weinert, Z. Iqbal, X. Didelot, H. Wang, F. Balloux

The paper analyzes the global spread of the mcr-1 gene by sequencing isolates and phylogenetic analysis, finding all mcr-1 elements originated from a single mobilization event in the mid-2000s.

bioRxiv · Nov 17, 2017Microbiology

The human oral microbiome is shaped by shared environment rather than genetics: evidence from a large family of closely-related individuals

L. Shaw, A. L. R. Ribeiro, A. P. Levine, N. Pontikos, F. Balloux, A. W. Segal, A. P. Roberts, A. Smith

This study shows that shared environment, not genetics, shapes the oral microbiome in a large family, with household effects persisting even after individuals move out.

bioRxiv · Apr 26, 2017Microbiology