Design of four component T=4 tetrahedral, octahedral, and icosahedral protein nanocages through programmed symmetry breaking
S. Lee, R. D. Kibler, Y. Hsia…·D. Baker
The paper designs T=4 protein nanocages with tetrahedral, octahedral, and icosahedral symmetries using pseudo-symmetrization of trimeric building blocks, resulting in structures with distinct subunits and interfaces.