Author

M. Bischoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 4 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Spengler· 2 shared K. Jacobs· 2 shared M. Hannig· 2 shared A. Aljohmani· 1 shared A. Fery· 1 shared A. Holtsch· 1 shared A. Kotecha· 1 shared A. M. M. A. Abdrabou· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

C. Spengler

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Author profile →

9 papers

Recent·Most cited

Extracellular release of a disintegrin and metalloproteinases orchestrates periodontal disease severity

A. Aljohmani, H. Heinze, F. G. Gharzia, B. Reda, A. M. M. A. Abdrabou, S. Becker, M. Bischoff, M. Hannig, D. Yildiz

The paper investigates the role of ADAM8 and ADAM10 in periodontal disease by analyzing their expression and activity in patients and in vitro models, finding that ADAM8 dysregulation may drive disease progression.

bioRxiv · Jul 21, 2023 · PreprintImmunology

The Secreted Tyrosine Phosphatase PtpA promotes Staphylococcus aureus Intramacrophagic Survival Through Decrease of the SUMOylation Host Response

N. Youssouf, M. Martin, M. Bischoff, P. Soubeyran, L. Gannoun-Zaki, V. Molle

This study identifies PtpA as a secreted phosphatase that reduces host SUMOylation by lowering Ubc9 levels, enhancing S. aureus survival during long-term infection.

bioRxiv · Aug 31, 2022 · PreprintMicrobiology

Hydroxyapatite pellets as versatile model surfaces for systematic studies on enamel

J. Mischo, T. Faidt, R. B. McMillan, J. Dudek, G. Gunaratnam, P. Bayenat, A. Holtsch, C. Spengler, F. Mueller, H. Haehl, M. Bischoff, M. Hannig, K. Jacobs

This study evaluates hydroxyapatite pellets as a model surface for studying bacterial adhesion, finding similar adhesion properties to enamel under various conditions.

bioRxiv · Jan 11, 2021 · PreprintBiophysics

T cell stiffness is enhanced upon formation of immunological synapse

P. Jung, X. Zhou, M. Bischoff, B. Qu

This study investigates T cell stiffness changes during immunological synapse formation using atomic force microscopy, revealing differential stiffening in lamellipodia and cell body.

bioRxiv · Jan 6, 2021Biophysics

The adhesion capability of S. aureus cells is heterogeneously distributed over the cell envelope

C. Spengler, E. Maikranz, B. A. Glatz, M. A. Klatt, H. Heintz, M. Bischoff, L. Santen, A. Fery, K. Jacobs

This study measures adhesion strength of S. aureus cells at different positions and finds heterogeneous adhesion profiles explained by distinct adhesive spots.

bioRxiv · Jan 5, 2021 · PreprintBiophysics

Single-particle cryo-EM at atomic resolution

T. Nakane, A. Kotecha, A. Sente, G. McMullan, S. Masiulis, P. M. G. E. Brown, I. T. Grigoras, L. Malinauskaite, T. Malinauskas, J. Miehling, L. Yu, D. Karia, E. V. Pechnikova, E. de Jong, J. Keizer, , S. Scheres

This paper demonstrates achieving atomic resolution cryo-EM structures for membrane proteins and apo-ferritin using advanced hardware, enabling detailed structural analysis and hydrogen bonding visualization.

Nature · Oct 21, 2020Peer-reviewedBiophysics

Filopodia-based contact stimulated collective migration drives tissue morphogenesis

M. Bischoff, R. Renkawitz-Pohl, S. Bogdan

The paper identifies filopodia-based contact stimulation as a mechanism driving collective migration in myotubes, distinct from lamellipodia-based CIL, and highlights the roles of Rac2, Cdc42, and Rho1 in this process.

bioRxiv · Oct 19, 2020Cell Biology

Cellular contractility coordinates cytoskeletal dynamics and cell behaviour during Drosophila abdominal morphogenesis

P. Pulido Companys, A. Norris, M. Bischoff

The paper investigates how cellular contractility coordinates cytoskeletal dynamics and cell behavior during Drosophila abdominal morphogenesis, finding that contractility levels and pulsatile actomyosin networks drive transitions between migration and constriction.

bioRxiv · Jun 28, 2019 · PreprintCell Biology

Apical caspase reporters uncover unknown stages of apoptosis and enable ready visualization of undead cells

L. A. Baena-Lopez, L. Arthurton, M. Bischoff, J.-P. Vincent, C. Alexandre, R. McGregor

The paper introduces new caspase reporters that reveal previously unknown stages of apoptosis and enable visualization of undead cells in Drosophila.

bioRxiv · Sep 17, 2018Cell Biology