Author

M. Chastney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. Ivaska· 2 shared A. Brech· 1 shared B. M. H. Bruininks· 1 shared B. Wilson· 1 shared C. Flett· 1 shared C. Lawless· 1 shared E. Hinde· 1 shared E. Kremneva· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

J. Ivaska

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Specialized actin nanoscale layers control focal adhesion turnover

R. Kumari, K. Ven, M. Chastney, J. Peranen, J. Arron, L. Almeida-Souza, E. Kremneva, R. Poincloux, T. L. Chew, P. W. Gunning, J. Ivaska, P. Lappalainen

The paper identifies two new nanoscale actin layers in focal adhesions, showing their distinct roles in adhesion maturation and disassembly through Tpm1.6 and Tpm3.2.

bioRxiv · Feb 15, 2023 · PreprintCell Biology

Regulation of cell dynamics by rapid transport of integrins through the biosynthetic pathway

M. Lerche, M. Mathieu, L. Malerod, N. M. Pedersen, H. Hamidi, M. Chastney, B. M. H. Bruininks, S. Kaptan, G. Jacquemet, I. Vattulainen, P. Roca-Cusachs, A. Brech, F. Perez, G. Boncompain, S. Miserey, J. Ivaska

This study shows that integrin transport through the biosynthetic pathway rapidly alters adhesion receptor availability, enabling localized cell spreading and focal adhesion growth.

bioRxiv · Jul 12, 2022Cell Biology

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

B. Wilson, J. Gemperle, C. Lawless, C. Flett, M. Hartshorn, E. Hinde, T. Harrison, M. Chastney, S. Taylor, J. Allen, P. T. Caswell

The paper uses proximity labeling to identify protein complexes associated with Rab4, Rab11a, and Rab25 in cancer cells, revealing their roles in endocytic recycling and cell migration.

bioRxiv · May 12, 2022Cell Biology