Author

J. Arron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:transcription & RNA processing· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

T. L. Chew· 4 shared A. dos Santos· 3 shared C. P. Toseland· 3 shared L. Wang· 3 shared M. L. Martin-Fernandez· 3 shared Y. Hari-Gupta· 3 shared N. Fili· 2 shared R. E. Gough· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCell Biology

T. L. Chew

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Specialized actin nanoscale layers control focal adhesion turnover

R. Kumari, K. Ven, M. Chastney, J. Peranen, J. Arron, L. Almeida-Souza, E. Kremneva, R. Poincloux, T. L. Chew, P. W. Gunning, J. Ivaska, P. Lappalainen

The paper identifies two new nanoscale actin layers in focal adhesions, showing their distinct roles in adhesion maturation and disassembly through Tpm1.6 and Tpm3.2.

bioRxiv · Feb 15, 2023 · PreprintCell Biology

Binding partners regulate unfolding of myosin VI to activate the molecular motor

A. dos Santos, N. Fili, Y. Hari-Gupta, R. E. Gough, L. Wang, M. L. Martin-Fernandez, J. Arron, E. Wait, T. L. Chew, C. P. Toseland

This study investigates how binding partners regulate myosin VI unfolding and activation through biochemical and single-molecule analyses of splice isoforms.

Biochemical Journal · Jul 4, 2022Peer-reviewedBiophysics

Actin nano-architecture of phagocytic podosomes

J. C. Herron, S. Hu, T. Watanabe, A. T. Nogueira, B. Liu, M. Kern, J. Arron, A. Taylor, M. Pablo, T.-L. Chew, T. C. Elston, K. M. Hahn

The paper uses advanced microscopy techniques to characterize the structure of phagocytic podosomes during frustrated phagocytosis, revealing their unique actin architecture and associated protein distributions.

bioRxiv · May 4, 2022Cell Biology

Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

A. dos Santos, D. E. Rollins, Y. Hari-Gupta, H. C. Reed, M. Du, S. Y. Z. Ru, K. Pidlisna, A. Stranger, F. Lorgat, I. Brown, K. Howland, J. Arron, L. Wang, P. J. Ellis, T. L. Chew, , C. P. Toseland

This study identifies NDP52's role in modulating RNA Polymerase II transcription by altering DNA conformation through direct dsDNA binding and interactions with chromatin regulators.

bioRxiv · Feb 1, 2022 · PreprintBiophysics

Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation.

Y. Hari-Gupta, N. Fili, A. dos Santos, A. W. Cook, R. E. Gough, H. C. W. Reed, L. Wang, J. Arron, T. Venit, E. Waite, A. Grosse-Berkenbusch, J. C. M. Gebhardt, P. Percipalle, T. L. Chew, M. L. Martin-Fernandez, C. P. Toseland

This study identifies nuclear myosin VI as a molecular anchor for RNA Polymerase II clusters, showing its role in maintaining transcription factory organization and gene expression.

bioRxiv · Apr 21, 2020Cell Biology