Author

M. E. Gentile

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. E. Vaughan· 2 shared N. P. Holcomb· 2 shared A. Gregorieff· 1 shared A. I. Weiner· 1 shared A. Jaquish· 1 shared A. Rochette· 1 shared C. V. Cosgriff· 1 shared D. Karo-Atar· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

A. E. Vaughan

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Author profile →

3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedMay 18, 2024

Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation

G. Zhao, M. E. Gentile, L. Xue…·A. E. Vaughan

This study identifies SPARCL1 as a pro-inflammatory mediator secreted by endothelial cells that worsens viral pneumonia by promoting macrophage activation and is elevated in severe COVID-19 cases.

DOI 10.1038/s41467-024-48589-3

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyJournal of Experimental MedicinePeer-reviewedAug 8, 2022

Direct reprogramming of the intestinal epithelium by parasitic helminths subverts type 2 immunity

D. Karo-Atar, S. Ouladan, T. Javkar…·I. L. King

This study shows that helminth infection reprograms intestinal epithelium into a fetal-like state, generating stem cells that inhibit type 2 immunity and promote helminth survival.

DOI 10.1084/jem.20212311

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivMar 10, 2022

Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

J. Barr, M. E. Gentile, S. Lee…·A. E. Vaughan

The paper identifies heterogeneous tuft cells in injured lungs that develop independently of Type 2 cytokines and are not essential for dysplastic repair.

DOI 10.7554/elife.78074

mousebulk RNA-seq

𝕏 PostBluesky