M. Gui

Decoding the anti-aging effect of retinol in reshaping the human skin microbiome niches

This study investigates how retinol affects the human skin microbiome and its role in retinol's anti-aging effects using phenomics, metagenomics, and metabolomics.

Structure and activation mechanism of the BBSome membrane-protein trafficking complex

The paper reports cryo-EM structures of the BBSome in inactive and active states, revealing how ARL6 binding activates the complex and how disease mutations disrupt its function.