M. Johnston

Habitat use differences mediate population threat exposure in white sturgeon

The paper examines habitat use differences in white sturgeon across life stages and links these patterns to population threats like angler pressure and red tide exposure.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

The paper identifies FOXO-dependent gene expression changes in Drosophila under hypoxia, revealing Hipk as a key regulator of hypoxia survival and uncovering FOXO's role in suppressing energy-intensive processes.

macroH2A2 shapes chromatin accessibility at enhancer elements in glioblastoma to modulate a targetable self-renewal epigenetic network

This study identifies macroH2A2 as a regulator of chromatin accessibility at enhancers in glioblastoma, showing that inhibiting Menin increases macroH2A2 and represses self-renewal.

CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme

This study identifies CASCADES, a lncRNA that regulates stemness in glioblastoma cancer stem cells by epigenetically controlling SOX2 expression.

Deciphering anomalous heterogeneous intracellular transport with neural networks

This paper develops a deep learning model to analyze heterogeneous intracellular transport by estimating Hurst exponents from short time series data, enabling dynamic segmentation of cellular structures.

Chitin perception in plasmodesmata identifies subcellular, context-specific immune signalling in plants

The paper investigates how chitin triggers distinct immune signaling at the plasmodesmal plasma membrane in plants, revealing specific receptor dynamics and signaling pathways.