M. R. King

This study uses single-fluorogen imaging to reveal that biomolecular condensates have hydrophobic internal environments and spatially inhomogeneous molecular organization.

This study identifies dynamical control as a mechanism enabling the formation of demixed biomolecular condensates by showing that asynchronous molecular production is required for their coexistence.

The paper shows that RanGTP directly regulates the augmin complex, which is a spindle assembly factor, to control branching microtubule nucleation during mitosis.

The paper identifies molecular grammars in intrinsically disordered regions of nucleolar proteins that drive phase separation to form nucleolar substructures.

This study identifies and characterizes intrinsic disorder in the N-terminal domains of MSL8, MSL9, and MSL10, showing distinct biophysical properties and environmental responsiveness.

The paper shows that chromosomes can nucleate microtubules to form spindles without centrosomes, using branching nucleation near kinetochores.

The paper shows that multivalent interactions enable motor-dependent protein accumulation at microtubule ends through disordered networks and liquid droplet formation in a reconstituted fission yeast system.

This study shows oxaliplatin-resistant colorectal cancer cells become more sensitive to TRAIL due to increased DR4 expression, palmitoylation, and lipid raft localization.

This study shows that importin-mediated interactions inhibit TPX2 phase separation, thereby regulating branching microtubule nucleation during spindle assembly.

The paper shows TPX2 phase separates with tubulin to enhance and spatially coordinate microtubule nucleation in vitro and in cytosol.